Cost-effectiveness of MRI strategies for early prostate cancer detection: a systematic review.

IF 1.5 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

Expert Review of Pharmacoeconomics & Outcomes Research Pub Date : 2025-08-07 DOI:10.1080/14737167.2025.2543464

Asal Sadat Niaraees Zavare, Atefeh Najafi Shahkoohi, Farhad Khalili, Aziz Rezapour, Somayeh Afshari, Samira Alipour, Ali Sarabi Asiabar

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引用次数: 0

Abstract

Objectives: The objective of this study is to evaluate the cost-effectiveness of different Magnetic Resonance Imaging strategies for the early detection of prostate cancer.

Methods: A comprehensive search was conducted up to 15 December 2024, utilizing databases such as PubMed and Scopus. The focus was on full economic evaluations, excluding non-English articles and reviews. The quality of the studies was assessed using the QHES checklist. The following data were extracted: settings, interventions, populations, types of economic evaluations, health outcomes, costs, and ICERs.

Results: Of the 110 articles that were assessed, 9 were selected for qualitative analysis, resulting in an overall high-quality score. The findings demonstrated that the range of MRI costs applied differed across countries. While the financial implications of non-screening are comparatively lower, the effectiveness of using screening strategies for early detection of cancer is superior to that of non-screening. Specifically, MRI was found to be more cost-effective than conventional methods. The utilization of MRI prior to biopsy has the potential to reduce unnecessary procedures while enhancing clinical cancer detection.

Conclusion: The economic viability of integrating advanced MRI techniques into prostate cancer screening is demonstrated, leading to enhanced patient outcomes by facilitating early detection and minimizing overtreatment.

Registration: PROSPERO (CRD42024572261).

查看原文本刊更多论文

早期前列腺癌MRI检测策略的成本效益：一项系统综述。

目的：本研究的目的是评估不同磁共振成像策略在前列腺癌早期检测中的成本效益。方法：利用PubMed、Scopus等数据库进行全面检索，检索截止到2024年12月15日。重点是全面的经济评估，不包括非英语文章和评论。使用QHES检查表评估研究的质量。提取了以下数据：环境、干预措施、人口、经济评估类型、健康结果、成本和ICERs。结果：在评估的110篇文章中，选择了9篇进行定性分析，得到了总体高质量的评分。研究结果表明，不同国家的MRI费用范围不同。虽然不筛查的财务影响相对较低，但使用筛查策略早期发现癌症的有效性优于不筛查。具体而言，MRI被发现比传统方法更具成本效益。在活检之前使用MRI有可能减少不必要的程序，同时增强临床癌症检测。结论：将先进的MRI技术整合到前列腺癌筛查中具有经济可行性，通过促进早期发现和减少过度治疗来提高患者的预后。注册：普洛斯彼罗（CRD42024572261）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Pharmacoeconomics & Outcomes Research HEALTH CARE SCIENCES & SERVICES-PHARMACOLOGY & PHARMACY

CiteScore

4.00

自引率

4.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Expert Review of Pharmacoeconomics & Outcomes Research (ISSN 1473-7167) provides expert reviews on cost-benefit and pharmacoeconomic issues relating to the clinical use of drugs and therapeutic approaches. Coverage includes pharmacoeconomics and quality-of-life research, therapeutic outcomes, evidence-based medicine and cost-benefit research. All articles are subject to rigorous peer-review. The journal adopts the unique Expert Review article format, offering a complete overview of current thinking in a key technology area, research or clinical practice, augmented by the following sections: Expert Opinion – a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points.