Evaluation of a patient decision aid for Japanese women with BRCA1/2 pathogenic variants: A preliminary study

IF 1.6 4区医学 Q2 NURSING

Japan Journal of Nursing Science Pub Date : 2025-08-06 DOI:10.1111/jjns.70017

Megumi Okawa, Naoko Arimori

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引用次数: 0

Abstract

Aim

This study aimed to evaluate a decision aid for Japanese women (J-DA) with BRCA1/2 pathogenic variants for supporting breast and ovarian cancer management decisions.

Methods

This study used a pre- and post-intervention design. The participants included Japanese women with BRCA1/2 pathogenic variants who needed to make a decision regarding breast and ovarian cancer management options.

Results

All 25 participants completed the pre- and posttests. There was a significant reduction in the decisional conflict scale and a significant increase in the knowledge score. Significant improvements were identified in the decisional conflict scale score (g = 0.60, p = .002) and knowledge score (g = −1.44, p < .001). Four weeks post-intervention, 96% of the participants had made a decision regarding the management options for breast or ovarian care.

Conclusions

The findings suggest that the decision aid (J-DA) positively supported the decision-making of the Japanese women with BRCA1/2 pathogenic variants. As this study apparently represents the first evaluation of a decision aid for this population, subsequent studies are anticipated to further confirm its clinical applicability and utility.

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日本女性BRCA1/2致病变异患者决策辅助评估：初步研究

目的：本研究旨在评估BRCA1/2致病变异的日本女性（J-DA）的决策辅助工具，以支持乳腺癌和卵巢癌的管理决策。方法采用干预前后设计。参与者包括患有BRCA1/2致病变异的日本妇女，她们需要决定乳腺癌和卵巢癌的治疗方案。结果25名受试者均完成了前、后测试。在决策冲突量表上有显著的减少，在知识得分上有显著的增加。决策冲突量表得分（g = 0.60, p = 0.002）和知识得分（g = - 1.44, p < 0.001）均有显著改善。干预4周后，96%的参与者对乳房或卵巢护理的管理选择做出了决定。结论决策辅助（J-DA）对日本BRCA1/2致病变异女性的决策具有积极的支持作用。由于这项研究显然代表了对这一人群的决策辅助的首次评估，预计后续研究将进一步证实其临床适用性和实用性。

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来源期刊

Japan Journal of Nursing Science 医学-护理

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Japan Journal of Nursing Science is the official English language journal of the Japan Academy of Nursing Science. The purpose of the Journal is to provide a mechanism to share knowledge related to improving health care and promoting the development of nursing. The Journal seeks original manuscripts reporting scholarly work on the art and science of nursing. Original articles may be empirical and qualitative studies, review articles, methodological articles, brief reports, case studies and letters to the Editor. Please see Instructions for Authors for detailed authorship qualification requirement.