Vacunación en la enfermedad pulmonar obstructiva crónica (EPOC): evidencia científica y estrategias para reducir riesgos

IF 1.7 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Revista clinica espanola Pub Date : 2025-08-01 DOI:10.1016/j.rce.2025.502330

Ó. Porto Fuentes , A. Muela Molinero , M.B. Alonso Ortiz

引用次数: 0

Abstract

Patients with chronic obstructive pulmonary disease (COPD) are more vulnerable to infections that may favor disease progression. Vaccination in COPD is an effective intervention that helps reduce infectious exacerbations, as well as associated morbidity and mortality.

In recent years, the use of new vaccines has become widespread, not only targeting specific infections but also contributing to long-lasting immunity and slowing the process of immune aging (immunosenescence).

Current clinical practice guidelines recommend the administration of six vaccines (against Streptococcus pneumoniae, influenza virus, SARS-CoV-2, respiratory syncytial virus, Bordetella pertussis, and varicella-zoster virus) for all COPD patients.

However, vaccination rates in many countries still fall short of the established targets. Therefore, it is crucial to design a specific vaccination schedule tailored for COPD patients.

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慢性阻塞性肺病（COPD）疫苗接种：科学证据和降低风险战略

慢性阻塞性肺疾病（COPD）患者更容易受到可能有利于疾病进展的感染。慢性阻塞性肺病的疫苗接种是一种有效的干预措施，有助于减少感染恶化以及相关的发病率和死亡率。近年来，新疫苗的广泛使用，不仅针对特定感染，而且有助于持久免疫和减缓免疫衰老过程（免疫衰老）。目前的临床实践指南建议对所有COPD患者接种六种疫苗（针对肺炎链球菌、流感病毒、SARS-CoV-2、呼吸道合胞病毒、百日咳博德泰拉和水痘带状疱疹病毒）。然而，许多国家的疫苗接种率仍未达到既定目标。因此，为COPD患者量身定制特定的疫苗接种计划至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista clinica espanola 医学-医学：内科

CiteScore

4.40

自引率

6.90%

发文量

审稿时长

28 days

期刊介绍： Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI). The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.