The options for delayed surgery – Is there evidence available for delayed genitoplasty in differences/disorders of sex development?

IF 6.1 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Best practice & research. Clinical endocrinology & metabolism Pub Date : 2025-07-01 DOI:10.1016/j.beem.2025.102024

Hedvig Engberg , Lisa Örtqvist , Gundela Holmdahl

引用次数: 0

Abstract

The question whether delaying genital surgery in individuals with differences/disorders of sex development is an option, or an even better option than early surgery, is complex and based on many considerations. The evidence must be considered poor for both alternatives. This review aims to evaluate some important outcome studies from the last two decades regarding the potential benefits of delayed genital surgery and explores the feasibility of performing male and female genitoplasty after the onset of puberty.

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延迟手术的选择-是否有证据表明延迟生殖器成形术可以治疗性发育的差异/障碍？

对于有性发育差异/障碍的个体，推迟生殖器手术是否是一种选择，或者比早期手术更好的选择，这个问题很复杂，需要考虑很多因素。这两种选择的证据都不够充分。本综述旨在评估过去二十年来关于延迟生殖器手术的潜在益处的一些重要结果研究，并探讨在青春期开始后进行男性和女性生殖器成形术的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best practice & research. Clinical endocrinology & metabolism 医学-内分泌学与代谢

CiteScore

11.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Best Practice & Research Clinical Endocrinology & Metabolism is a serial publication that integrates the latest original research findings into evidence-based review articles. These articles aim to address key clinical issues related to diagnosis, treatment, and patient management. Each issue adopts a problem-oriented approach, focusing on key questions and clearly outlining what is known while identifying areas for future research. Practical management strategies are described to facilitate application to individual patients. The series targets physicians in practice or training.