Charles Thivolet , Zoé Henry , Nathalie Bendelac , Sylvie Villar Fimbel
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引用次数: 0
Abstract
Objective
This study analyzed the determinants of weight gain among participants initiating an automated insulin delivery (AID) system.
Research design and methods
In this observational study, we evaluated 928 persons with type 1 diabetes initiating an insulin pump therapy, including 467 with AID, 98 with pumps with predictive low-glucose suspend (PLGS) algorithm and 363 initiating a sensor-augmented pump (SAP).
Results
After 3 months, median (95CI) TIR increased from 50.69 % [49.2–52.3] to 67.9 % [66.7–69.1] in the AID group and HbA1c levels showed a mean reduction of 0.82 %. AID resulted in equivalent body weight gain to SAP and PLGS despite significant improvements in glucose control. Multivariable analysis revealed that weight gain was linked to baseline HbA1C (P < 0.001) and age but not to the type of pump system. During follow-up, percentage increase in body weight at 12 months were similar between groups
Conclusions
In persons with T1D, AID did not increase weight gain in comparison to other pump systems.
期刊介绍:
A high quality scientific journal with an international readership
Official publication of the SFD, Diabetes & Metabolism, publishes high-quality papers by leading teams, forming a close link between hospital and research units. Diabetes & Metabolism is published in English language and is indexed in all major databases with its impact factor constantly progressing.
Diabetes & Metabolism contains original articles, short reports and comprehensive reviews.