Rony Moon BA, MS, Emma Zeng MD, Richard Brach MD, Michael E. Lazarus MD, FACP, FRCP
{"title":"Co-occurrence of five chemotherapy induced nail findings","authors":"Rony Moon BA, MS, Emma Zeng MD, Richard Brach MD, Michael E. Lazarus MD, FACP, FRCP","doi":"10.1002/jhm.70149","DOIUrl":null,"url":null,"abstract":"<p>A 58-year-old man with acute myeloid leukemia developed five distinct new fingernail changes after chemotherapy. These include onycholysis, palpable transverse depressions across his fingernails, diffuse melanonychia, transverse, nonblanching white bands, and thin white transverse lines all caused by his chemotherapy regimen. It is uncommon to find all five of these physical exam findings simultaneously. We describe the underlying pathophysiology for hospital-based clinicians and highlight their transient course.</p>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"20 10","pages":"1149-1150"},"PeriodicalIF":2.3000,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of hospital medicine","FirstCategoryId":"3","ListUrlMain":"https://shmpublications.onlinelibrary.wiley.com/doi/10.1002/jhm.70149","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
A 58-year-old man with acute myeloid leukemia developed five distinct new fingernail changes after chemotherapy. These include onycholysis, palpable transverse depressions across his fingernails, diffuse melanonychia, transverse, nonblanching white bands, and thin white transverse lines all caused by his chemotherapy regimen. It is uncommon to find all five of these physical exam findings simultaneously. We describe the underlying pathophysiology for hospital-based clinicians and highlight their transient course.
期刊介绍:
JHM is a peer-reviewed publication of the Society of Hospital Medicine and is published 12 times per year. JHM publishes manuscripts that address the care of hospitalized adults or children.
Broad areas of interest include (1) Treatments for common inpatient conditions; (2) Approaches to improving perioperative care; (3) Improving care for hospitalized patients with geriatric or pediatric vulnerabilities (such as mobility problems, or those with complex longitudinal care); (4) Evaluation of innovative healthcare delivery or educational models; (5) Approaches to improving the quality, safety, and value of healthcare across the acute- and postacute-continuum of care; and (6) Evaluation of policy and payment changes that affect hospital and postacute care.