The changing neglected tropical disease landscape in Africa: implications for policy, practice, and strengthening health systems.

IF 2.7
Health affairs scholar Pub Date : 2025-07-31 eCollection Date: 2025-07-01 DOI:10.1093/haschl/qxaf136
Philip Downs, Andrew Tate, Danny Harvey, Margaret C Baker
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Abstract

Introduction: Mass drug administration (MDA) has reached up to 1 billion people annually to combat neglected tropical diseases (NTDs). This study explores the evolving NTD landscape in Africa amid shifting disease patterns, funding cuts, and universal health coverage goals.

Methods: We analyzed data from ESPEN and Sightsavers databases to assess historical trends and forecast future treatment needs.

Results: By 2027, few or no MDAs for lymphatic filariasis and trachoma will be required and MDAs for onchocerciasis dropped sharply after 2024. In contrast, schistosomiasis and soil-transmitted helminths continue to require widespread MDA.

Conclusion: To secure elimination gains, remaining MDAs must be completed and broader health systems approaches adopted.

Abstract Image

非洲被忽视的热带病形势的变化:对政策、实践和加强卫生系统的影响。
导言:为防治被忽视的热带病,每年向多达10亿人提供大规模药物给药。本研究探讨了在疾病模式转变、资金削减和全民健康覆盖目标的背景下,非洲不断演变的非传染性疾病形势。方法:我们分析来自ESPEN和Sightsavers数据库的数据,评估历史趋势并预测未来的治疗需求。结果:到2027年,淋巴丝虫病和沙眼的MDAs将很少或不需要,盘尾丝虫病的MDAs在2024年后急剧下降。相反,血吸虫病和土壤传播蠕虫继续需要广泛的丙二醛。结论:为了确保消除成果,必须完成剩余的MDAs,并采用更广泛的卫生系统方法。
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