Tran Ngoc An Huynh, Darren Trinh, Janan Chandrananth, James Sewell
{"title":"An unusual distal tibial metastasis from urothelial carcinoma: A case report.","authors":"Tran Ngoc An Huynh, Darren Trinh, Janan Chandrananth, James Sewell","doi":"10.14440/bladder.2024.0077","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Bladder cancer (BCa) frequently metastasizes to bones, typically affecting the spine and pelvis.</p><p><strong>Case presentation: </strong>Presented here is a case of rare extensive distal tibia metastasis in an 84-year-old female with invasive high-grade urothelial carcinoma, who suffered from rapidly progressive ankle pain and reduced mobility. Imaging and biopsy confirmed metastatic urothelial carcinoma in the tibia, which was managed with surgical fixation and palliative radiotherapy. Although bone metastases in BCa commonly affect other sites, clinicians should consider atypical locations like the tibia in patients with unexplained bone pain.</p><p><strong>Conclusion: </strong>Early diagnosis and intervention are essential for improving patient outcomes and quality of life.</p>","PeriodicalId":72421,"journal":{"name":"Bladder (San Francisco, Calif.)","volume":"12 1","pages":"e21200041"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12308123/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bladder (San Francisco, Calif.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14440/bladder.2024.0077","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Bladder cancer (BCa) frequently metastasizes to bones, typically affecting the spine and pelvis.
Case presentation: Presented here is a case of rare extensive distal tibia metastasis in an 84-year-old female with invasive high-grade urothelial carcinoma, who suffered from rapidly progressive ankle pain and reduced mobility. Imaging and biopsy confirmed metastatic urothelial carcinoma in the tibia, which was managed with surgical fixation and palliative radiotherapy. Although bone metastases in BCa commonly affect other sites, clinicians should consider atypical locations like the tibia in patients with unexplained bone pain.
Conclusion: Early diagnosis and intervention are essential for improving patient outcomes and quality of life.