{"title":"A single centre study on prevalence of anemia in children and adolescents with atopic dermatitis and its associated factors.","authors":"N Ravindran, S Krishnasamy, A Jamil, G Preamala","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Chronic inflammation, food avoidance, and the use of systemic immunosuppressants are associated with anemia in patients with atopic dermatitis (AD). This study aimed to determine the prevalence of anemia among children and adolescents with AD, the type of anemia, and its predisposing factors.</p><p><strong>Materials and methods: </strong>This is a cross-sectional study. Patients aged ≤18 years with AD were included in the study. The exclusion criteria were malignancy, chronic organ failure, and haematological diseases. Dietary patterns and nutrient intake were determined using a 3-day dietary recall. AD severity was assessed using a scoring tool known as Scoring Atopic Dermatitis (SCORAD). Peripheral blood counts, iron studies, and serum B12 and folate levels were determined.</p><p><strong>Results: </strong>A total of 77 patients were recruited for this study. The mean age was 8.58±5.26 years with 43(55.8%) boys and 34(44.2%) girls. Most (58.4%) were from economic bottomtier households with incomes below RM4850. Food avoidance was common (55.8%), primarily for shellfish (37.7%), nuts (33.8%), and eggs (22.1%). The prevalence of anemia was 58.4%, and 71.1% was due to iron deficiency. Younger age, male sex, underweight, and lower intakes of iron, protein, and fat were significantly associated with anemia. There was no association between the severity with anemia.</p><p><strong>Conclusion: </strong>The high prevalence of iron deficiency anemia in patients with AD was likely due to the lower intake of food restrictions compounded with chronic inflammation in AD.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 4","pages":"390-396"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Malaysia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Introduction: Chronic inflammation, food avoidance, and the use of systemic immunosuppressants are associated with anemia in patients with atopic dermatitis (AD). This study aimed to determine the prevalence of anemia among children and adolescents with AD, the type of anemia, and its predisposing factors.
Materials and methods: This is a cross-sectional study. Patients aged ≤18 years with AD were included in the study. The exclusion criteria were malignancy, chronic organ failure, and haematological diseases. Dietary patterns and nutrient intake were determined using a 3-day dietary recall. AD severity was assessed using a scoring tool known as Scoring Atopic Dermatitis (SCORAD). Peripheral blood counts, iron studies, and serum B12 and folate levels were determined.
Results: A total of 77 patients were recruited for this study. The mean age was 8.58±5.26 years with 43(55.8%) boys and 34(44.2%) girls. Most (58.4%) were from economic bottomtier households with incomes below RM4850. Food avoidance was common (55.8%), primarily for shellfish (37.7%), nuts (33.8%), and eggs (22.1%). The prevalence of anemia was 58.4%, and 71.1% was due to iron deficiency. Younger age, male sex, underweight, and lower intakes of iron, protein, and fat were significantly associated with anemia. There was no association between the severity with anemia.
Conclusion: The high prevalence of iron deficiency anemia in patients with AD was likely due to the lower intake of food restrictions compounded with chronic inflammation in AD.
期刊介绍：
Published since 1890 this journal originated as the Journal of the Straits Medical Association. With the formation of the Malaysian Medical Association (MMA), the Journal became the official organ, supervised by an editorial board. Some of the early Hon. Editors were Mr. H.M. McGladdery (1960 - 1964), Dr. A.A. Sandosham (1965 - 1977), Prof. Paul C.Y. Chen (1977 - 1987). It is a scientific journal, published quarterly and can be found in medical libraries in many parts of the world. The Journal also enjoys the status of being listed in the Index Medicus, the internationally accepted reference index of medical journals. The editorial columns often reflect the Association''s views and attitudes towards medical problems in the country. The MJM aims to be a peer reviewed scientific journal of the highest quality. We want to ensure that whatever data is published is true and any opinion expressed important to medical science. We believe being Malaysian is our unique niche; our priority will be for scientific knowledge about diseases found in Malaysia and for the practice of medicine in Malaysia. The MJM will archive knowledge about the changing pattern of human diseases and our endeavours to overcome them. It will also document how medicine develops as a profession in the nation. We will communicate and co-operate with other scientific journals in Malaysia. We seek articles that are of educational value to doctors. We will consider all unsolicited articles submitted to the journal and will commission distinguished Malaysians to write relevant review articles. We want to help doctors make better decisions and be good at judging the value of scientific data. We want to help doctors write better, to be articulate and precise.
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