Bibliometric insights into transforming the management of rheumatoid arthritis: three decades of progress against opportunistic infections.

IF 3.4 4区 医学 Q2 RHEUMATOLOGY
Wenzhong Hu, Yun Xu
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引用次数: 0

Abstract

Objectives: The aim of this study was to investigate the research trends, patterns of opportunistic infections in rheumatoid arthritis (RA) and their impact on patient management strategies, especially in the context of the widespread use of DMARDs.

Methods: Research papers on RA and opportunistic infections were analysed by performing a literature search in the Web of Science Core Collection (WoSCC) database, covering the period from January 1, 1994 to December 31, 2023. Bibliometric analyses were performed using VOS viewer and Cite Space software, including country and institution analyses, journal and co-citation journal analyses, author and co-citation author analyses, and key word co-occurrence and clustering analyses.

Results: Two hundred and ninety-three research papers were analysed, and it was found that research publications on RA-associated opportunistic infections have shown a general upward trend over the past three decades, with a significant increase especially between 2007 and 2021. Japan, the United States, and China have the highest research output in this area, with institutions such as Yang Ming University and Taichung Veterans General Hospital being more active. Key word analysis revealed 'infection', 'risk', 'treatment', and 'infliximab' as research hotspots. Cluster analysis showed that tuberculosis, latent tuberculosis infection and hepatitis B virus were the focus of attention.

Conclusions: Research on opportunistic infections in RA has shown a clear trend of growth and extensive international collaboration, reflecting a deep understanding of the risk of opportunistic infections in RA patients treated with DMARDs. Future studies should strengthen the identification of high-risk patient groups, the use of biomarkers, the balance of safety and efficacy in treatment regimens, and patient education to promote the optimisation of RA management strategies.

文献计量学见解转化类风湿关节炎的管理:三十年的进展对抗机会性感染。
目的:本研究的目的是调查类风湿关节炎(RA)的研究趋势、机会性感染的模式及其对患者管理策略的影响,特别是在DMARDs广泛使用的背景下。方法:对Web of Science Core Collection (WoSCC)数据库1994年1月1日至2023年12月31日期间有关RA和机会性感染的研究论文进行文献检索分析。使用VOS viewer和Cite Space软件进行文献计量分析,包括国家和机构分析、期刊和共被引期刊分析、作者和共被引作者分析、关键词共现和聚类分析。结果:对293篇研究论文进行了分析,发现在过去三十年中,与ra相关的机会性感染的研究出版物总体呈上升趋势,特别是在2007年至2021年期间显著增加。日本、美国和中国在这一领域的研究产出最高,其中阳明大学和台中退伍军人总医院等机构更为活跃。关键词分析显示,“感染”、“风险”、“治疗”和“英夫利昔单抗”是研究热点。聚类分析显示,结核病、潜伏性结核感染和乙型肝炎病毒是关注的重点。结论:对RA机会性感染的研究呈现出明显的增长趋势和广泛的国际合作,反映了对DMARDs治疗RA患者机会性感染风险的深刻认识。未来的研究应加强高风险患者群体的识别、生物标志物的使用、治疗方案安全性和有效性的平衡以及患者教育,以促进RA管理策略的优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
18.90%
发文量
377
审稿时长
3-6 weeks
期刊介绍: Clinical and Experimental Rheumatology is a bi-monthly international peer-reviewed journal which has been covering all clinical, experimental and translational aspects of musculoskeletal, arthritic and connective tissue diseases since 1983.
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