{"title":"Temporal changes in sucrose phantoms for magnetic resonance imaging: effects of preparation temperatures.","authors":"Yasuo Takatsu, Akiyoshi Iwase, Naoki Hayashi, Masataka Oita, Kenmei Mizutani, Mizuki Ito, Tosiaki Miyati","doi":"10.1007/s12194-025-00940-z","DOIUrl":null,"url":null,"abstract":"<p><p>This study investigated the effects of preparation temperature and usage period on the relaxation times and apparent diffusion coefficients (ADC) of sucrose phantoms to enhance imaging reliability. Phantoms were prepared using 10% sucrose solutions at 20, 50, and 80 °C. T1 and T2 relaxation times and ADC were monitored over 80 days using magnetic resonance imaging on a 1.5 T system. T2 relaxation time in 50 °C solutions increased from 245.5 to 1579 ms, while 80 °C solutions showed the highest stability (coefficient of variation ≈ 1.8%). T1 relaxation time changes were minimal, and ADC decreased at an average rate of 2.19 × 10<sup>-6</sup> mm<sup>2</sup>/s per day. Bacteria were observed in the sucrose solution, and higher protein concentrations were strongly correlated with decreased 1/T2. In conclusion, sucrose phantoms exhibited temperature-dependent stability, with 80 °C preparations providing the most reliable T2 relaxation time.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiological Physics and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12194-025-00940-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
This study investigated the effects of preparation temperature and usage period on the relaxation times and apparent diffusion coefficients (ADC) of sucrose phantoms to enhance imaging reliability. Phantoms were prepared using 10% sucrose solutions at 20, 50, and 80 °C. T1 and T2 relaxation times and ADC were monitored over 80 days using magnetic resonance imaging on a 1.5 T system. T2 relaxation time in 50 °C solutions increased from 245.5 to 1579 ms, while 80 °C solutions showed the highest stability (coefficient of variation ≈ 1.8%). T1 relaxation time changes were minimal, and ADC decreased at an average rate of 2.19 × 10-6 mm2/s per day. Bacteria were observed in the sucrose solution, and higher protein concentrations were strongly correlated with decreased 1/T2. In conclusion, sucrose phantoms exhibited temperature-dependent stability, with 80 °C preparations providing the most reliable T2 relaxation time.
期刊介绍：
The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
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