Modified Heidelberg (Buchler's) Technique of Pancreaticojejunostomy after Pancreaticoduodenectomy and Its Implications on Postoperative Pancreatic Fistula.

Karthik Chalamalasetti, Sugaprakash Sankareswaran, Prabhakaran Raju, Sugumar Chidambaranathan
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Abstract

Introduction: With the advancement in surgical techniques, the mortality after pancreaticoduodenectomy (PD) has significantly decreased, but the morbidity remains the same. The occurrence of postoperative pancreatic fistula (POPF) directly affects morbidity, and many pancreatic reconstruction techniques have been developed to decrease the rates of clinically relevant postoperative pancreatic fistula (CR-POPF).

Materials and methods: Our modified Heidelberg (Buchler's) technique differs from the original in the aspect that continuous sutures rather than intermittent sutures are used in all layers of the anastomosis. The outcomes of this technique were analyzed, and factors associated with POPF and CR-POPF were determined. A retrospective analysis was performed on data from 78 patients for whom the modified Heidelberg technique was used to perform pancreatojejunostomy (PJ) after PD at our institute between 2017 and 2023. In subgroup analysis, the incidence of POPF was compared between the initial phase when other PJ techniques were still practiced at our institute and the period after the technique was standardized.

Results: The incidence of CR-POPF was 6.4%, and the overall incidence of POPF was 33.3%. Postpancreatectomy hemorrhage occurred in 7.6% of the patients, and the 30-day mortality rate was 5.1%. Following standardization, the incidence of CR-POPF was significantly reduced to 4%. Prior biliary stenting and soft pancreas were risk factors for the development of POPF (p < 0.05).

Conclusion: The outcomes of PD tended to improve with the use of a single pancreatic anastomosis technique. Our modification of the Heidelberg technique of PJ is easy to perform and produces outcomes equivalent to the original Heidelberg technique. Our analysis showed that prior biliary stenting, soft pancreas, and intraoperative pancreatic duct stent placement increased the incidence of POPF, and CR-POPF was significantly associated with morbidity.

How to cite this article: Chalamalasetti K, Sankareswaran S, Raju P, et al. Modified Heidelberg (Buchler's) Technique of Pancreaticojejunostomy after Pancreaticoduodenectomy and Its Implications on Postoperative Pancreatic Fistula. Euroasian J Hepato-Gastroenterol 2025;15(1):100-106.

Abstract Image

胰十二指肠切除术后胰空肠吻合术的改良Heidelberg (Buchler’s)技术及其对术后胰瘘的影响。
导论:随着手术技术的进步,胰十二指肠切除术(PD)的死亡率显著降低,但发病率不变。术后胰瘘(POPF)的发生直接影响到发病率,许多胰腺重建技术已经被开发出来以降低临床相关的术后胰瘘(CR-POPF)的发生率。材料和方法:我们改良的Heidelberg (Buchler’s)技术与原始技术的不同之处在于在所有层吻合中使用连续缝合而不是间歇缝合。分析该技术的结果,并确定与POPF和CR-POPF相关的因素。回顾性分析2017年至2023年我院PD术后采用改良Heidelberg技术行胰空肠吻合术(PJ)的78例患者的数据。在亚组分析中,比较我院仍在使用其他PJ技术的初始阶段与技术标准化后的POPF发生率。结果:CR-POPF发病率为6.4%,总发病率为33.3%。7.6%的患者发生胰腺切除术后出血,30天死亡率为5.1%。标准化后,CR-POPF的发生率显著降低至4%。胆道支架置入术和软胰是发生POPF的危险因素(p < 0.05)。结论:单胰吻合术有改善PD预后的趋势。我们对PJ的Heidelberg技术的修改易于执行,并且产生与原始Heidelberg技术等效的结果。我们的分析显示,既往胆道支架置入术、软胰和术中胰管支架置入术增加了POPF的发生率,CR-POPF与发病率显著相关。本文引用方式:Chalamalasetti K, Sankareswaran S, Raju P,等。胰十二指肠切除术后胰空肠吻合术的改良Heidelberg (Buchler’s)技术及其对术后胰瘘的影响。中华肝病杂志;2015;15(1):100-106。
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