{"title":"Asthma and chronic obstructive pulmonary disease in the intensive care unit","authors":"Craig Johnston, Paul Nixon","doi":"10.1016/j.mpaic.2025.05.008","DOIUrl":null,"url":null,"abstract":"<div><div>The prevalence of asthma and chronic obstructive pulmonary disease is increasing worldwide. Patients who require intensive care management for acute exacerbations of these conditions represent a particular challenge. The requirement for invasive mechanical ventilation is associated with many pitfalls, as evidenced by the higher mortality rate of patients undergoing this intervention. This article describes the initial management, as well as escalating respiratory support and advanced pharmacological therapies, and the current evidence supporting these. In particular, the concept of dynamic hyperinflation is addressed as well as ventilation strategies that should be employed to prevent the development of complications.</div></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"26 8","pages":"Pages 507-514"},"PeriodicalIF":0.3000,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029925001092","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The prevalence of asthma and chronic obstructive pulmonary disease is increasing worldwide. Patients who require intensive care management for acute exacerbations of these conditions represent a particular challenge. The requirement for invasive mechanical ventilation is associated with many pitfalls, as evidenced by the higher mortality rate of patients undergoing this intervention. This article describes the initial management, as well as escalating respiratory support and advanced pharmacological therapies, and the current evidence supporting these. In particular, the concept of dynamic hyperinflation is addressed as well as ventilation strategies that should be employed to prevent the development of complications.
期刊介绍:
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.