{"title":"Mid-term Results of Aneurysmorrhaphy for Enlargement After EVAR.","authors":"Yuko Wada, Yuki Takagi, Shuji Chino, Tohru Mikoshiba, Haruki Tanaka, Hajime Ichimura, Noburo Ohashi, Tatsuichiro Seto","doi":"10.1016/j.jvs.2025.07.025","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Although endovascular aneurysm repair (EVAR) is a standard treatment for abdominal aortic aneurysms, postprocedural aneurysm expansion caused by types II and V endoleaks remains challenging. Aortic graft replacement is a definitive solution but is associated with high morbidity and mortality-especially in elderly patients. Aneurysmorrhaphy has emerged as a less invasive alternative. This study evaluated the mid-term outcomes of aneurysmorrhaphy after EVAR and identified factors associated with aneurysm re-expansion.</p><p><strong>Methods: </strong>This retrospective study included 50 patients who underwent aneurysmorrhaphy after EVAR in 2016-2021. Indications included aneurysm expansion due to type II or V endoleaks. Surgery was performed using the transperitoneal approach with aneurysm sac opening, thrombus removal, and plication without graft replacement. Intraoperative endoleak diagnosis and preoperative computed tomography (CT) findings were compared. Survival, reintervention, and risk factors for re-expansion were assessed by Kaplan-Meier analysis and logistic regression.</p><p><strong>Results: </strong>The intraoperative morbidity rate was 6%, the perioperative mortality rate was 0%, and the postoperative morbidity rate was 12%. Compared with preoperative CT findings, the diagnosis was changed in 13 cases (26%). Among the cases initially diagnosed as Type II EL alone, 2 cases had concomitant Type Ib EL, and 7 cases were Type 3b EL. The mean follow-up period was 4.5 years. The 5-year survival and reintervention-free rates were 90% and 92%, respectively. Notably, the 5-year freedom from aneurysm re-expansion rate was only 84%. Residual endoleaks and dead-space areas were notable predictors of re-expansion. Receiver operating characteristic analysis identified a dead-space threshold of 70%, above which re-expansion risk was significantly higher.</p><p><strong>Conclusions: </strong>Aneurysmorrhaphy is a viable alternative to graft replacement for post-EVAR aneurysm expansion, especially in high-risk patients. However, the risk of re-expansion remains critical, particularly when dead-space reduction is inadequate. Careful patient selection and further research can optimize long-term outcomes.</p>","PeriodicalId":17475,"journal":{"name":"Journal of Vascular Surgery","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jvs.2025.07.025","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Although endovascular aneurysm repair (EVAR) is a standard treatment for abdominal aortic aneurysms, postprocedural aneurysm expansion caused by types II and V endoleaks remains challenging. Aortic graft replacement is a definitive solution but is associated with high morbidity and mortality-especially in elderly patients. Aneurysmorrhaphy has emerged as a less invasive alternative. This study evaluated the mid-term outcomes of aneurysmorrhaphy after EVAR and identified factors associated with aneurysm re-expansion.
Methods: This retrospective study included 50 patients who underwent aneurysmorrhaphy after EVAR in 2016-2021. Indications included aneurysm expansion due to type II or V endoleaks. Surgery was performed using the transperitoneal approach with aneurysm sac opening, thrombus removal, and plication without graft replacement. Intraoperative endoleak diagnosis and preoperative computed tomography (CT) findings were compared. Survival, reintervention, and risk factors for re-expansion were assessed by Kaplan-Meier analysis and logistic regression.
Results: The intraoperative morbidity rate was 6%, the perioperative mortality rate was 0%, and the postoperative morbidity rate was 12%. Compared with preoperative CT findings, the diagnosis was changed in 13 cases (26%). Among the cases initially diagnosed as Type II EL alone, 2 cases had concomitant Type Ib EL, and 7 cases were Type 3b EL. The mean follow-up period was 4.5 years. The 5-year survival and reintervention-free rates were 90% and 92%, respectively. Notably, the 5-year freedom from aneurysm re-expansion rate was only 84%. Residual endoleaks and dead-space areas were notable predictors of re-expansion. Receiver operating characteristic analysis identified a dead-space threshold of 70%, above which re-expansion risk was significantly higher.
Conclusions: Aneurysmorrhaphy is a viable alternative to graft replacement for post-EVAR aneurysm expansion, especially in high-risk patients. However, the risk of re-expansion remains critical, particularly when dead-space reduction is inadequate. Careful patient selection and further research can optimize long-term outcomes.
期刊介绍:
Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.