Mid-term Results of Aneurysmorrhaphy for Enlargement After EVAR.

IF 3.6 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Yuko Wada, Yuki Takagi, Shuji Chino, Tohru Mikoshiba, Haruki Tanaka, Hajime Ichimura, Noburo Ohashi, Tatsuichiro Seto
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引用次数: 0

Abstract

Objective: Although endovascular aneurysm repair (EVAR) is a standard treatment for abdominal aortic aneurysms, postprocedural aneurysm expansion caused by types II and V endoleaks remains challenging. Aortic graft replacement is a definitive solution but is associated with high morbidity and mortality-especially in elderly patients. Aneurysmorrhaphy has emerged as a less invasive alternative. This study evaluated the mid-term outcomes of aneurysmorrhaphy after EVAR and identified factors associated with aneurysm re-expansion.

Methods: This retrospective study included 50 patients who underwent aneurysmorrhaphy after EVAR in 2016-2021. Indications included aneurysm expansion due to type II or V endoleaks. Surgery was performed using the transperitoneal approach with aneurysm sac opening, thrombus removal, and plication without graft replacement. Intraoperative endoleak diagnosis and preoperative computed tomography (CT) findings were compared. Survival, reintervention, and risk factors for re-expansion were assessed by Kaplan-Meier analysis and logistic regression.

Results: The intraoperative morbidity rate was 6%, the perioperative mortality rate was 0%, and the postoperative morbidity rate was 12%. Compared with preoperative CT findings, the diagnosis was changed in 13 cases (26%). Among the cases initially diagnosed as Type II EL alone, 2 cases had concomitant Type Ib EL, and 7 cases were Type 3b EL. The mean follow-up period was 4.5 years. The 5-year survival and reintervention-free rates were 90% and 92%, respectively. Notably, the 5-year freedom from aneurysm re-expansion rate was only 84%. Residual endoleaks and dead-space areas were notable predictors of re-expansion. Receiver operating characteristic analysis identified a dead-space threshold of 70%, above which re-expansion risk was significantly higher.

Conclusions: Aneurysmorrhaphy is a viable alternative to graft replacement for post-EVAR aneurysm expansion, especially in high-risk patients. However, the risk of re-expansion remains critical, particularly when dead-space reduction is inadequate. Careful patient selection and further research can optimize long-term outcomes.

EVAR术后动脉瘤扩大的中期结果分析。
目的:虽然血管内动脉瘤修复(EVAR)是腹主动脉瘤的标准治疗方法,但II型和V型内漏引起的术后动脉瘤扩张仍然具有挑战性。主动脉瓣置换术是一种明确的解决方案,但与高发病率和死亡率相关,特别是在老年患者中。动脉瘤缝合术已成为一种侵入性较小的替代方法。本研究评估了EVAR后动脉瘤吻合的中期结果,并确定了与动脉瘤再扩张相关的因素。方法:本回顾性研究包括2016-2021年间50例EVAR术后动脉瘤缝合患者。适应症包括II型或V型内漏导致的动脉瘤扩张。手术采用经腹膜入路,打开动脉瘤囊,去除血栓,不更换移植物。术中内漏诊断与术前CT检查结果比较。通过Kaplan-Meier分析和logistic回归评估患者的生存、再干预和再扩张的危险因素。结果:术中发病率为6%,围手术期死亡率为0%,术后发病率为12%。与术前CT表现相比,有13例(26%)改变了诊断。在最初仅诊断为II型EL的病例中,2例合并Ib型EL, 7例合并3b型EL。平均随访时间为4.5年。5年生存率为90%,无再干预率为92%。值得注意的是,5年无动脉瘤再扩张率仅为84%。残余内漏和死区面积是再扩张的显著预测因子。接受者工作特征分析确定死区阈值为70%,高于该阈值再扩张风险显著增加。结论:对于evar后动脉瘤扩张患者,尤其是高危患者,动脉瘤吻合术是替代移植物的可行选择。但是,重新扩张的风险仍然很大,特别是在减少死区不足的情况下。仔细的患者选择和进一步的研究可以优化长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.70
自引率
18.60%
发文量
1469
审稿时长
54 days
期刊介绍: Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.
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