Long-Term Patterns in Automated Insulin Delivery and Carbohydrate Announcement: A 24-Month Follow-Up.

IF 5.7 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Estelle Godard, Alfred Penfornis, Coralie Amadou
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引用次数: 0

Abstract

We evaluated long-term (24 months) consistency in carbohydrate counting and meal announcements among Control-IQ users using two parameters: auto-bolus percentage (i.e., automatic correction boluses divided by total boluses) and daily carbohydrate announcement (DCA). In this single-center retrospective cohort study (October 2021-October 2024), we analyzed trends in auto-bolus percentage-alongside DCA and metabolic control-and its associations with age, sex, DCA, and time in range (TIR) using mixed-effects linear models. Among 2751 person-quarters (57% women, mean age 37 years), the mean auto-bolus percentage was 61% and increased by 0.4% per quarter (P < 0.001). DCA declined from 132 to 100 g/day, while TIR slightly decreased from 61% to 58%. Auto-bolus percentage was inversely associated with age, TIR, and DCA, with the latter association strengthening over time. The modest change in TIR suggests sustained effectiveness of automated insulin delivery despite decreasing carbohydrate reporting-likely reflecting adaptive user behavior.

自动胰岛素输送和碳水化合物的长期模式:24个月的随访。
我们使用两个参数评估Control-IQ用户长期(24个月)碳水化合物计数和膳食公告的一致性:自动丸量百分比(即自动校正丸量除以总丸量)和每日碳水化合物公告(DCA)。在这项单中心回顾性队列研究(2021年10月至2024年10月)中,我们使用混合效应线性模型分析了自动服药百分比(以及DCA和代谢控制)的趋势及其与年龄、性别、DCA和范围时间(TIR)的关系。在2751人/季度中(57%为女性,平均年龄37岁),平均自动丸率为61%,每季度增加0.4% (P < 0.001)。DCA从132 g/d下降到100 g/d, TIR从61%下降到58%。自动丸率与年龄、TIR和DCA呈负相关,随着时间的推移,后者的相关性增强。TIR的适度变化表明,尽管碳水化合物报告减少,但自动胰岛素输送的持续有效性可能反映了适应性用户行为。
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来源期刊
Diabetes technology & therapeutics
Diabetes technology & therapeutics 医学-内分泌学与代谢
CiteScore
10.60
自引率
14.80%
发文量
145
审稿时长
3-8 weeks
期刊介绍: Diabetes Technology & Therapeutics is the only peer-reviewed journal providing healthcare professionals with information on new devices, drugs, drug delivery systems, and software for managing patients with diabetes. This leading international journal delivers practical information and comprehensive coverage of cutting-edge technologies and therapeutics in the field, and each issue highlights new pharmacological and device developments to optimize patient care.
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