{"title":"Nanoscale Force Measurement with Optical Tweezers: Applications and Future Prospects in Biophotonics (Advanced Optical Materials 21/2025)","authors":"Yinyue Ji, Zhengtian Jin, Jianxing Zhou, Yuhang Peng, Xiaoqi Dai, Yili Zhong, Jinming Zhang, Haoyu Liu, Meiting Wang, Junle Qu, Ho-Pui Ho, Shuwen Zeng, Yuye Wang, Jiajie Chen, Yonghong Shao","doi":"10.1002/adom.70070","DOIUrl":null,"url":null,"abstract":"<p><b>Nanoscale Force Measurement</b></p><p>An optical trapping generated from a Gaussian laser beam traps a microsphere, which interacts with red blood cells, DNA, and proteins, enabling precise force measurements with piconewton-level precision. The fundamental principle of force detection is highlighted by the equation F = kΔx, where F is the force, k is the trap stiffness, and Δx is the displacement of the microsphere. This technique provides a powerful tool for probing biomechanical interactions in nanoscience and biophysics. More details can be found in article 2403140 by Shuwen Zeng, Yuye Wang, Jiajie Chen, and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":116,"journal":{"name":"Advanced Optical Materials","volume":"13 21","pages":""},"PeriodicalIF":7.2000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adom.70070","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Optical Materials","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adom.70070","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Nanoscale Force Measurement
An optical trapping generated from a Gaussian laser beam traps a microsphere, which interacts with red blood cells, DNA, and proteins, enabling precise force measurements with piconewton-level precision. The fundamental principle of force detection is highlighted by the equation F = kΔx, where F is the force, k is the trap stiffness, and Δx is the displacement of the microsphere. This technique provides a powerful tool for probing biomechanical interactions in nanoscience and biophysics. More details can be found in article 2403140 by Shuwen Zeng, Yuye Wang, Jiajie Chen, and co-workers.
期刊介绍:
Advanced Optical Materials, part of the esteemed Advanced portfolio, is a unique materials science journal concentrating on all facets of light-matter interactions. For over a decade, it has been the preferred optical materials journal for significant discoveries in photonics, plasmonics, metamaterials, and more. The Advanced portfolio from Wiley is a collection of globally respected, high-impact journals that disseminate the best science from established and emerging researchers, aiding them in fulfilling their mission and amplifying the reach of their scientific discoveries.