Honglei Wang, Jing Guan, Jia Zeng, Ting Wang, Xu Lang, Rong Fu
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引用次数: 0
Abstract
Background: Acute promyelocytic leukemia (APL) is prone to hemorrhage and thrombosis during onset and induction treatment. Occasionally, severe and rare thrombosis can occur, which deserves our attention. Such as Budd-Chiari syndrome (BCS). BCS is a rare and severe disease caused by occlusion of the hepatic veins. Ascites, abdominal pain, and abnormal liver function are the first manifestations of this disease.
Case presentation: We report the case of a high-risk patient with APL with acute liver failure and massive ascites during induction therapy due to BCS. He was in a critical condition between life-threatening bleeding tendency and thrombosis. The patient was successfully treated with thrombectomy of the right hepatic vein and balloon dilatation therapy, which provided time for APL treatment.
Conclusion: Our case highlights an uncommon venous thrombosis due to APL. We hope to provide some new treatment options for clinicians.
期刊介绍：
Hematology is an international journal publishing original and review articles in the field of general hematology, including oncology, pathology, biology, clinical research and epidemiology. Of the fixed sections, annotations are accepted on any general or scientific field: technical annotations covering current laboratory practice in general hematology, blood transfusion and clinical trials, and current clinical practice reviews the consensus driven areas of care and management.
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