Continuous preparation of 50 nm emulsions of soybean oil using a novel temperature-controllable ultrasonic tandem emulsifying unit

IF 3.4 2区 农林科学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Jingjing Li , Zehong Fang , Hao Tang , Lizheng Liu , Wenqiang Shang , Xueqing Huang , Xiaojing Zhu , Giancarlo Cravotto , Zhengya Dong , Zhilin Wu
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Abstract

Nanoemulsions with approximately 50 nm droplets possess extensive applications in food, medicine, cosmetics, etc., attributable to their transparency, remarkable stability, and high bioavailability. A novel temperature-controllable 21.1 kHz ultrasonic tandem emulsifying unit (USTE) was designed and used to prepare around 50 nm emulsions based on the synergistic effect of ultrasonic cavitation and continuous flow. Due to the use of glass-jacketed beakers, the metal particle contamination of the nanoemulsions caused by the conventional metal ultrasonic probes was essentially eliminated. Besides, the cavitation erosion to the glass-jacketed beakers was diminished by applying the low ultrasonic power of the USTE. The effects of flow rate (0.5–6 mL/min), temperature (45–65 °C), ultrasonic power (11–24 W), glycerol, and types and concentrations of surfactants (Tween-80, Span-80, PEG-400) on the droplet sizes (DS) and polydispersity index (PDI) of soybean oil nanoemulsions were investigated. At a flow rate of 1 or 2 mL/min, 5.4 % concentration of surfactant (Span-80/Tween-80 (28/72 w/w, HLB12), volume ratio of the aqueous phase to the oil phase (A/O) of 9:1, translucent soybean oil nanoemulsions with a average DS of 42 or 55 nm and a PDI of 0.138 or 0.152 were obtained at first-grade and second-grade ultrasonic emulsification power of 20 W/22 W at 55 °C. The obtained nanoemulsions remained highly steady after being stored at 4 °C and 25 °C for 220 days. Compared with a high-pressure homogenizer and an ultrasonic microreactor, the nanoemulsions obtained using the USTE boasted better quality with higher energy efficiency.
利用新型温控超声串联乳化装置连续制备50 nm大豆油乳剂
纳米乳液具有大约50个 纳米液滴,由于其透明度,卓越的稳定性和高生物利用度,在食品,医药,化妆品等领域具有广泛的应用。设计了一种温度可控的21.1 kHz超声串联乳化装置(USTE),利用超声空化和连续流动的协同作用,制备了50 nm左右的乳化液。由于使用了玻璃套烧杯,基本上消除了传统金属超声探头对纳米乳造成的金属颗粒污染。此外,利用USTE的低超声功率减小了玻璃套烧杯的空化侵蚀。考察了流速(0.5 ~ 6 mL/min)、温度(45 ~ 65 ℃)、超声功率(11 ~ 24 W)、甘油和表面活性剂(Tween-80、Span-80、PEG-400)的种类和浓度对豆油纳米乳液滴大小(DS)和多分散性指数(PDI)的影响。在流量为1或2 mL/min,表面活性剂(Span-80/ twen -80 (28/72 w/w, HLB12)浓度为5.4 %,水相与油相体积比(a /O)为9:1的条件下,在55 ℃下,一级和二级超声乳化功率为20 w/ 22 w时,可制得平均DS为42或55 nm, PDI为0.138或0.152的半透明大豆油纳米乳。在4 °C和25 °C条件下保存220天后,得到的纳米乳保持高度稳定。与高压均质机和超声微反应器相比,USTE制备的纳米乳质量更好,能效更高。
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来源期刊
Food and Bioproducts Processing
Food and Bioproducts Processing 工程技术-工程:化工
CiteScore
9.70
自引率
4.30%
发文量
115
审稿时长
24 days
期刊介绍: Official Journal of the European Federation of Chemical Engineering: Part C FBP aims to be the principal international journal for publication of high quality, original papers in the branches of engineering and science dedicated to the safe processing of biological products. It is the only journal to exploit the synergy between biotechnology, bioprocessing and food engineering. Papers showing how research results can be used in engineering design, and accounts of experimental or theoretical research work bringing new perspectives to established principles, highlighting unsolved problems or indicating directions for future research, are particularly welcome. Contributions that deal with new developments in equipment or processes and that can be given quantitative expression are encouraged. The journal is especially interested in papers that extend the boundaries of food and bioproducts processing. The journal has a strong emphasis on the interface between engineering and food or bioproducts. Papers that are not likely to be published are those: • Primarily concerned with food formulation • That use experimental design techniques to obtain response surfaces but gain little insight from them • That are empirical and ignore established mechanistic models, e.g., empirical drying curves • That are primarily concerned about sensory evaluation and colour • Concern the extraction, encapsulation and/or antioxidant activity of a specific biological material without providing insight that could be applied to a similar but different material, • Containing only chemical analyses of biological materials.
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