Laparoscopic sleeve gastrectomy and nutritional deficiency: A comprehensive longitudinal analysis.

IF 1.1 4区 医学 Q3 SURGERY
Shahbaz Bashir, Zubair Gul Lone, Yawar Nazir, Bilal Ahmad Wagay, Gowhar Aziz Bhat, Mubashir Ahmad Shah
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引用次数: 0

Abstract

Introduction: Laparoscopic sleeve gastrectomy (LSG) represents a cornerstone in the surgical management of morbid obesity. While the procedure effectively reduces weight and improves obesity-related comorbidities, the anatomical alterations inherent to LSG can lead to significant nutritional challenges. These modifications in gastrointestinal physiology may result in various micronutrient deficiencies, particularly affecting iron, Vitamin B12 and folate status.

Patients and methods: We conducted a prospective cohort study of 70 patients undergoing LSG at our tertiary care centre. Participants underwent comprehensive nutritional assessment at baseline and regular intervals postoperatively (6, 12 and 24 months). We measured serum levels of key micronutrients, including iron, Vitamin B12 and folate, while simultaneously tracking supplement adherence. Statistical analysis incorporated both univariate and multivariate approaches to identify patterns and risk factors for nutritional deficiencies.

Results: Our analysis revealed distinct gender-specific patterns in nutritional deficiencies. Female patients demonstrated significantly higher rates of iron deficiency throughout the study period, with prevalence rates of 58%, 50% and 36% at 6, 12 and 24 months, respectively. Vitamin B12 deficiency showed a progressive increase in both genders, while supplement adherence declined markedly from 96% at 6 months to 42% at 24 months. Multivariate analysis identified female gender, younger age and poor supplement adherence as significant risk factors for nutritional deficiencies.

Conclusion: Post-LSG nutritional deficiencies present a significant clinical challenge, particularly for female patients. Our findings emphasise the critical importance of long-term nutritional monitoring and the need for targeted supplementation and adherence-enhancing intervention strategies to improve supplement adherence.

腹腔镜袖式胃切除术与营养缺乏:一项全面的纵向分析。
简介:腹腔镜袖胃切除术(LSG)是病态肥胖手术治疗的基石。虽然该手术有效地减轻了体重并改善了肥胖相关的合并症,但LSG固有的解剖改变可能导致严重的营养挑战。胃肠道生理学的这些变化可能导致各种微量营养素缺乏,特别是影响铁、维生素B12和叶酸状态。患者和方法:我们对在三级护理中心接受LSG治疗的70例患者进行了前瞻性队列研究。参与者在基线和术后定期(6、12和24个月)接受全面的营养评估。我们测量了关键微量营养素的血清水平,包括铁、维生素B12和叶酸,同时跟踪补充剂的依从性。统计分析结合了单变量和多变量方法来确定营养缺乏的模式和风险因素。结果:我们的分析揭示了不同性别的营养缺乏模式。在整个研究期间,女性患者的缺铁率明显更高,在6个月、12个月和24个月时的患病率分别为58%、50%和36%。维生素B12缺乏症在两性中呈渐进式增加,而补充剂依从性从6个月时的96%明显下降到24个月时的42%。多变量分析表明,女性性别、年龄较小和缺乏补充剂依从性是营养缺乏的重要危险因素。结论:lsg后的营养缺乏是一个重大的临床挑战,特别是对女性患者。我们的研究结果强调了长期营养监测的重要性,以及有针对性的补充和增强依从性的干预策略的必要性,以提高补充剂的依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.70
自引率
0.00%
发文量
151
审稿时长
36 weeks
期刊介绍: Journal of Minimal Access Surgery (JMAS), the official publication of Indian Association of Gastrointestinal Endo Surgeons, launched in early 2005. The JMAS, a quarterly publication, is the first English-language journal from India, as also from this part of the world, dedicated to Minimal Access Surgery. The JMAS boasts an outstanding editorial board comprising of Indian and international experts in the field.
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