The efficacy of autologous blood patch pleurodesis for prolonged air leak after anatomical lung resection.

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian Journal of Thoracic and Cardiovascular Surgery Pub Date : 2025-08-01 Epub Date: 2025-04-21 DOI:10.1007/s12055-025-01938-3

Ahmed Magdy Elmezayen, Ahmed Osama, Taha Bin Esmael, Ahmed Mousa, Ayman Amer, Amal Said Elbendary, Hatem Naase

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引用次数: 0

Abstract

Background: Prolonged air leak (PAL) is a well-known issue that frequently results in extended hospitalization following pulmonary lobectomy. There have been many suggestions for preventing air leaks, but no one method has yet achieved definitive success. The purpose of this research was to determine the efficacy of autologous blood patch pleurodesis (ABPP) to treat PAL.

Methods: This retrospective study was conducted on 60 patients aged ≥ 18 years, involving both sexes, with PAL after pulmonary lobectomy. Patients were categorized into two groups: group A received ABPP for PAL, and group B did not receive ABPP.

Results: Group A had a significantly lower invasive procedure rate than group B (P = 0.023). The incidence of reoperation was not significantly different between the two groups. Ten (33.33%) patients in group B required computed tomography (CT) scans to identify the residual air pockets, of whom six (20%) patients treated with bronchoscopy and CT-guided chest drain insertion in the residual air pocket. The mean ± standard deviation (SD) of chest tube removal after surgery was 7.77 ± 1.52 days in group A and 9.53 ± 3.48 days in group B (P = 0.014). Group A had a significantly shorter hospital stay after surgery than group B (P < 0.05). In linear regression, the amount of blood used was an independent predictor of chest tube removal after surgery (P = 0.003), while age, smoking, global initiative for obstructive lung disease, diabetes mellitus, and the Charlson comorbidity index were not.

Conclusions: ABPP is a prompt, safe, and successful method to treat post-lobectomy PAL, which shortens the time patients spend in the hospital and allows for the early removal of chest tubes.

Graphical abstract:

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自体血贴胸膜固定术治疗解剖肺切除术后长时间漏气的疗效观察。

背景：长时间空气泄漏（PAL）是一个众所周知的问题，经常导致肺叶切除术后住院时间延长。有许多防止空气泄漏的建议，但没有一种方法取得了决定性的成功。本研究的目的是确定自体血贴片胸膜切除术（ABPP）治疗PAL的疗效。方法：回顾性研究60例年龄≥18岁的男女肺叶切除术后PAL患者。将患者分为两组：A组接受PAL的ABPP治疗，B组不接受ABPP治疗。结果：A组有创手术率显著低于B组（P = 0.023）。两组再手术发生率无明显差异。B组10例（33.33%）患者需要CT扫描识别残留气穴，其中6例（20%）患者行支气管镜检查并在CT引导下将胸腔引流液插入残留气穴。术后拔胸管时间A组为7.77±1.52 d， B组为9.53±3.48 d （P = 0.014）。A组术后住院时间明显短于B组（P P = 0.003），而年龄、吸烟、阻塞性肺疾病总体主动性、糖尿病和Charlson合病指数无显著差异。结论：ABPP是一种及时、安全、成功的治疗肺叶切除术后PAL的方法，缩短了患者住院时间，并允许早期拔除胸管。图形化的简介:

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来源期刊

Indian Journal of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.20

自引率

14.30%

发文量

141

期刊介绍： The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.