Effects of mindfulness-based interventions on mental health among women with fetal loss: A systematic review and meta-analysis

IF 2.6 3区医学 Q1 NURSING

Midwifery Pub Date : 2025-07-15 DOI:10.1016/j.midw.2025.104520

Xin Wang , Ying Luo , Ying Gao , Jun-yan Li , Yan-Qiong Ouyang , Rong Wang

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引用次数: 0

Abstract

Background

Mindfulness-based interventions (MBIs) have shown potential in reducing maternal negative emotions, but their effectiveness for women with fetal loss requires further investigation. This study aimed to evaluate the effects of MBIs on mental health outcomes among these women.

Methods

Randomized controlled trials (RCTs) on MBIs for women with fetal loss were retrieved from eight databases, covering literature from inception to ^{January 21, 2025}. Outcomes included depression, anxiety, and post-traumatic growth. Risk of bias was assessed using Cochrane RoB 1.0, and meta-analyses were performed using Review Manager 5.4.

Results

Ten RCTs were included. MBIs significantly improve depression (SMD=1.01, 95 %CI (0.60,1.41), p < 0.01), anxiety (SMD=1.24, 95 %CI (0.57, 1.91), p < 0.01), stress (SMD=0.99, 95 %CI (0.11, 1.86), p = 0.03) and post-traumatic growth (MD=19.67, 95 %CI (10.96, 28.38), p < 0.01) in women with fetal loss. Subgroup analyses were feasible only for depression and anxiety. MBIs significantly reduced depressive symptoms in both women with pre-existing psychological symptoms (SMD=0.85, p < 0.01) and those without (SMD=1.07, p < 0.01), with no significant difference by intervention duration (p > 0.05). For anxiety symptoms, MBIs were effective only in women without symptoms (SMD=1.57, p < 0.01). Short-duration MBIs (≤4 weeks, SMD=2.59, p < 0.01) showed greater effects than long-duration MBIs (>4 weeks, SMD=0.74, p < 0.01).

Limitations

There are few high-quality RCTs, small sample sizes, and a lack of long-term follow-up.

Conclusions

MBIs effectively improve mental health in women with fetal loss, with short-duration effects exceeding long-duration ones. These findings support the integration of MBIs into psychosocial care, particularly for women with pre-existing psychological symptoms, and highlight the need to refine intervention strategies.

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正念干预对流产妇女心理健康的影响：系统回顾和荟萃分析

基于正念的干预（mbi）已经显示出减少母亲负面情绪的潜力，但其对胎儿丢失妇女的有效性需要进一步研究。本研究旨在评估MBIs对这些女性心理健康结果的影响。方法从8个数据库中检索mbi治疗流产妇女的随机对照试验（rct），涵盖从建立到2025年1月21日的文献。结果包括抑郁、焦虑和创伤后成长。使用Cochrane RoB 1.0评估偏倚风险，使用Review Manager 5.4进行meta分析。结果纳入10项随机对照试验。mbi显著改善抑郁(SMD=1.01, 95% CI (0.60,1.41), p <；0.01)，焦虑(SMD=1.24, 95% CI (0.57, 1.91), p <；0.01)、应激（SMD=0.99, 95% CI (0.11, 1.86), p = 0.03）、创伤后成长(MD=19.67, 95% CI (10.96, 28.38), p <；0.01)。亚组分析仅适用于抑郁和焦虑。mbbs显著减轻两名已有心理症状女性的抑郁症状(SMD=0.85, p <；0.01)和无SMD组(SMD=1.07, p <；0.01)，干预时间差异无统计学意义(p >；0.05)。对于焦虑症状，mbi仅对无症状的女性有效(SMD=1.57, p <；0.01)。短期mbi(≤4周，SMD=2.59, p <；0.01)比长期mbi (>；4周，SMD=0.74, p <；0.01)。局限性：高质量的随机对照试验很少，样本量小，缺乏长期随访。结论smbis能有效改善胎儿流产妇女的心理健康，且短期效果优于长期效果。这些发现支持将MBIs纳入社会心理护理，特别是对已有心理症状的妇女，并强调需要完善干预策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Midwifery 医学-护理

CiteScore

4.50

自引率

7.40%

发文量

221

审稿时长

13.4 weeks

期刊介绍： Midwifery publishes the latest peer reviewed international research to inform the safety, quality, outcomes and experiences of pregnancy, birth and maternity care for childbearing women, their babies and families. The journal’s publications support midwives and maternity care providers to explore and develop their knowledge, skills and attitudes informed by best available evidence. Midwifery provides an international, interdisciplinary forum for the publication, dissemination and discussion of advances in evidence, controversies and current research, and promotes continuing education through publication of systematic and other scholarly reviews and updates. Midwifery articles cover the cultural, clinical, psycho-social, sociological, epidemiological, education, managerial, workforce, organizational and technological areas of practice in preconception, maternal and infant care. The journal welcomes the highest quality scholarly research that employs rigorous methodology. Midwifery is a leading international journal in midwifery and maternal health with a current impact factor of 1.861 (© Thomson Reuters Journal Citation Reports 2016) and employs a double-blind peer review process.