Photophysical Properties of Substituted Zinc Phthalocyanine-Dextran Systems

IF 3 4区化学 Q3 CHEMISTRY, PHYSICAL

ChemPhotoChem Pub Date : 2025-04-17 DOI:10.1002/cptc.202400385

Tamara Potlog, Ion Lungu, Anton Airinei, Radu Tigoianu

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Abstract

This study presents the synthesis of tetracarboxy ZnPc/dextran and octacarboxy ZnPc/dextran solutions and the investigation of their photophysical properties using UV–vis, transient absorption (TA), and emission spectroscopy. Nanosecond TA measurements are conducted using pump–probe techniques. ZnPc(COOH)₄ derivative exhibits efficient fluorescence, room-temperature phosphorescence in dimethyl sulfoxide/H₂O solution, with a quantum efficiency of 14.8% and lifetimes of 1.18 and 8.89 μs. The addition of dextran to ZnPc(COOH)₈ broadens the splitting of the two subbands in the Q band, leading to a characteristically strong far-redshift in the UV–vis absorption spectrum compared to the ZnPc(COOH)₄/dextran (DX) system. The triplet-state properties of ZnPc(COOH)₄/DX and ZnPc(COOH)₈/DX systems with an absorption region within the phototherapeutic window, the average lifetimes values of 4.86 and 5.17 μs, respectively, reveal them attractive as photosensitizing materials in photodynamic therapy. TA spectra of ZnPc(COOH)₄/DX and ZnPc(COOH)₈/DX conjugates measured at a pump pulse of 355 nm show positive and negative signals, indicating triplet–triplet (T–T) absorption and triplet–singlet (T–S) emission.

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取代酞菁锌-右旋糖酐体系的光物理性质

本文研究了四羧基ZnPc/葡聚糖和八羧基ZnPc/葡聚糖溶液的合成，并利用紫外可见光谱、瞬态吸收光谱和发射光谱对其光物理性质进行了研究。纳秒TA测量是使用泵探针技术进行的。ZnPc(COOH)4衍生物在二甲亚砜/H2O溶液中表现出高效的荧光和室温磷光，量子效率为14.8%，寿命分别为1.18和8.89 μs。与ZnPc(COOH)4/dextran （DX）体系相比，右旋糖酐加入ZnPc(COOH)8使Q波段两个亚带的分裂变宽，导致紫外-可见吸收光谱具有明显的远红移。ZnPc(COOH)4/DX和ZnPc(COOH)8/DX在光疗窗口内具有吸收区的三重态性质，平均寿命分别为4.86和5.17 μs，表明它们是光动力治疗中具有吸引力的光敏材料。在355nm的泵浦脉冲下，ZnPc(COOH)4/DX和ZnPc(COOH)8/DX共轭物的TA光谱显示出正、负信号，表明三重-三重态（T-T）吸收和三重-单重态（T-S）发射。

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来源期刊

ChemPhotoChem Chemistry-Physical and Theoretical Chemistry

CiteScore

5.80

自引率

5.40%

发文量

165

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