Feasibility randomised controlled trial of a brief psychological intervention for adolescents with borderline personality disorder symptoms delivered with schools and colleges.

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Jon Wilson, Brioney Gee, Nicola Martin, Sarah Maxwell, Jamie Murdoch, Tim Clarke, Allan Clark, David Turner, Thando Katangwe-Chigamba, Peter B Jones, Peter Fonagy
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引用次数: 0

Abstract

Background: There is an urgent need for accessible interventions to facilitate early intervention for young people with borderline personality disorder (BPD) symptoms. Existing evidence-based interventions for adolescent BPD are highly resource-intensive, and few young people with BPD symptoms have access to timely treatment. We adapted a brief psychological treatment for adolescent BPD symptoms previously provided within secondary mental health services for delivery within schools and colleges. This study aimed to assess the feasibility of evaluating the effectiveness and cost-effectiveness of this intervention (BEST (brief education support treatment)) in a future randomised controlled trial (RCT).

Methods: The feasibility RCT involved 12 schools and colleges. Eligible participants were aged 13-18 years and self-reported BPD symptoms above a clinical threshold and a history of repeated self-harm. Over 9 months, 32 participants were randomised to receive either the BEST intervention plus treatment as usual (TAU) or TAU alone. Participants were assessed at baseline and 12 and 24 weeks. A mixed-methods process evaluation was conducted.

Results: Recruitment was slower than anticipated, but participant retention was high (89.5% at 12 weeks and 73.7% at 24 weeks). Performance of all outcome measures was satisfactory. Fidelity of intervention delivery was high (93.5% adherent), and we did not identify any evidence of contamination of the control arm. The intervention was perceived by staff and young people as beneficial to participants, practitioners and the wider school/college and therefore highly acceptable.

Limitations: The study was disrupted by the closure of schools and colleges in response to the COVID-19 pandemic. This reduced the window for participant recruitment and limited data collection.

Conclusions: The intervention was delivered successfully within schools and colleges and was acceptable to staff and young people. The findings provide support for continuing this programme of research and should inform the design of a future evaluation of intervention outcomes.

Trial registration number: ISRCTN16862589.

Abstract Image

Abstract Image

对有边缘性人格障碍症状的青少年进行短期心理干预的可行性随机对照试验。
背景:迫切需要可获得的干预措施,以促进对边缘型人格障碍(BPD)症状的年轻人的早期干预。针对青少年BPD的现有循证干预措施是高度资源密集型的,很少有有BPD症状的年轻人能够获得及时的治疗。我们对以前在二级心理健康服务机构提供的针对青少年BPD症状的简短心理治疗进行了调整,以便在学校和大学内提供。本研究旨在评估在未来随机对照试验(RCT)中评估这种干预(BEST(简短教育支持治疗)的有效性和成本效益的可行性。方法:可行性随机对照试验纳入12所高等学校。符合条件的参与者年龄在13-18岁之间,自我报告的BPD症状高于临床阈值,并有重复自残史。在9个月的时间里,32名参与者随机接受BEST干预加常规治疗(TAU)或单独接受TAU治疗。在基线、12周和24周时对参与者进行评估。采用混合方法进行工艺评价。结果:招募比预期慢,但参与者保留率高(12周时为89.5%,24周时为73.7%)。所有结果指标的表现均令人满意。干预递送的保真度很高(93.5%的依从性),我们没有发现对照组污染的任何证据。工作人员和年轻人认为这种干预对参与者、从业者和更广泛的学校/学院都是有益的,因此是高度可接受的。局限性:该研究因学校和大学为应对COVID-19大流行而关闭而中断。这减少了参与者招募的窗口期和有限的数据收集。结论:该干预措施在学校和学院内成功实施,并为工作人员和青少年所接受。研究结果为继续开展这一研究项目提供了支持,并应为未来干预结果评估的设计提供信息。试验注册号:ISRCTN16862589。
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来源期刊
Pilot and Feasibility Studies
Pilot and Feasibility Studies Medicine-Medicine (miscellaneous)
CiteScore
2.70
自引率
5.90%
发文量
241
审稿时长
9 weeks
期刊介绍: Pilot and Feasibility Studies encompasses all aspects of the design, conduct and reporting of pilot and feasibility studies in biomedicine. The journal publishes research articles that are intended to directly influence future clinical trials or large scale observational studies, as well as protocols, commentaries and methodology articles. The journal also ensures that the results of all well-conducted, peer-reviewed, pilot and feasibility studies are published, regardless of outcome or significance of findings. Pilot and feasibility studies are increasingly conducted prior to a full randomized controlled trial. However, these studies often lack clear objectives, many remain unpublished, and there is confusion over the meanings of the words “pilot” and “feasibility”. Pilot and Feasibility Studies provides a forum for discussion around this key aspect of the scientific process, and seeks to ensure that these studies are published, so as to complete the publication thread for clinical research.
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