Exploring the bifunctional role of Pd/ZrO2-TiO2 in the production of secondary amines via reductive amination of furfural

IF 4.7 2区化学 Q2 CHEMISTRY, PHYSICAL

Applied Catalysis A: General Pub Date : 2025-07-18 DOI:10.1016/j.apcata.2025.120455

Alex A. Fernández-Andrade , John A. Vergara , Daviel Gómez , Daniela González-Vera , Cristian H. Campos , Joan M. Rodríguez-Díaz , Luis E. Arteaga-Pérez

{"title":"Exploring the bifunctional role of Pd/ZrO2-TiO2 in the production of secondary amines via reductive amination of furfural","authors":"Alex A. Fernández-Andrade , John A. Vergara , Daviel Gómez , Daniela González-Vera , Cristian H. Campos , Joan M. Rodríguez-Díaz , Luis E. Arteaga-Pérez","doi":"10.1016/j.apcata.2025.120455","DOIUrl":null,"url":null,"abstract":"<div><div>Environmental concerns and the pressing need for sustainable technologies have increased the interest in furfural (FUR) amination as an environmentally friendly alternative to current petroleum-based amination processes. Here we systematically investigate the bifunctional effect of Pd/ZrO<sub>2</sub>-TiO<sub>2</sub> for the one-pot reductive amination of FUR with aniline (ANI) using H<sub>2</sub> as the reducing agent. The structural characterization of Pd/ZrO<sub>2</sub>-TiO<sub>2</sub> indicated Ti atom substitutions by Zr, highly dispersed Zr sites, and modulated acidity. The Pd/ZrO<sub>2</sub>-TiO<sub>2</sub> catalyst was active and stable for converting FUR into N-furfurylaniline (FFA) following a sequential reaction map, involving the formation of an intermediate imine (IME), with subsequent hydrogenation. The water formed in the first reaction step does not interfere in the reaction performance as confirmed by FTIR-ATR <em>in situ</em> measurements. Finally, the effectiveness of the catalyst was explained by the presence of acid sites which enhance C<img>O and N = H activation, with subsequent hydrogenation promoted by Pd<sup>0</sup> sites.</div></div>","PeriodicalId":243,"journal":{"name":"Applied Catalysis A: General","volume":"705 ","pages":"Article 120455"},"PeriodicalIF":4.7000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Catalysis A: General","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0926860X25003564","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Environmental concerns and the pressing need for sustainable technologies have increased the interest in furfural (FUR) amination as an environmentally friendly alternative to current petroleum-based amination processes. Here we systematically investigate the bifunctional effect of Pd/ZrO₂-TiO₂ for the one-pot reductive amination of FUR with aniline (ANI) using H₂ as the reducing agent. The structural characterization of Pd/ZrO₂-TiO₂ indicated Ti atom substitutions by Zr, highly dispersed Zr sites, and modulated acidity. The Pd/ZrO₂-TiO₂ catalyst was active and stable for converting FUR into N-furfurylaniline (FFA) following a sequential reaction map, involving the formation of an intermediate imine (IME), with subsequent hydrogenation. The water formed in the first reaction step does not interfere in the reaction performance as confirmed by FTIR-ATR in situ measurements. Finally, the effectiveness of the catalyst was explained by the presence of acid sites which enhance CO and N = H activation, with subsequent hydrogenation promoted by Pd⁰ sites.

查看原文本刊更多论文

探索Pd/ZrO2-TiO2在糠醛还原胺化生产仲胺中的双功能作用

环境问题和对可持续技术的迫切需求增加了对糠醛（FUR）胺化的兴趣，作为当前石油基胺化工艺的一种环境友好型替代品。本文以H2为还原剂，系统研究了Pd/ZrO2-TiO2在苯胺（ANI）一锅还原氨化FUR中的双功能作用。Pd/ZrO2-TiO2的结构表征为Ti原子被Zr取代，Zr位点高度分散，酸度调节。Pd/ZrO2-TiO2催化剂在连续反应图中将FUR转化为n -呋喃苯胺（FFA），包括中间亚胺（IME）的形成，并随后加氢，具有活性和稳定性。FTIR-ATR原位测量证实，在第一反应步骤中形成的水不会干扰反应性能。最后，该催化剂的有效性是由于酸位的存在增强了CO和N = H的活化，随后Pd0位点促进了加氢。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Applied Catalysis A: General 化学-环境科学

CiteScore

9.00

自引率

5.50%

发文量

415

审稿时长

24 days

期刊介绍： Applied Catalysis A: General publishes original papers on all aspects of catalysis of basic and practical interest to chemical scientists in both industrial and academic fields, with an emphasis onnew understanding of catalysts and catalytic reactions, new catalytic materials, new techniques, and new processes, especially those that have potential practical implications. Papers that report results of a thorough study or optimization of systems or processes that are well understood, widely studied, or minor variations of known ones are discouraged. Authors should include statements in a separate section "Justification for Publication" of how the manuscript fits the scope of the journal in the cover letter to the editors. Submissions without such justification will be rejected without review.