A Review on the Application and Mechanism of Low Temperature Plasma in the Field of Tumor Therapy.

IF 2.8 4区 医学 Q3 ONCOLOGY
Technology in Cancer Research & Treatment Pub Date : 2025-01-01 Epub Date: 2025-07-15 DOI:10.1177/15330338251356439
Meng Zhang, Dong Yang, Xiangyu Meng, Yuanlin Liu, Tao Zhang
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引用次数: 0

Abstract

Low temperature plasma (LTP), as an emerging cancer treatment technology, has shown significant therapeutic potential due to its unique physical and chemical properties and biological effects. This article reviews the basic characteristics of LTP and its multiple mechanisms of application in tumor treatment. LTP can induce various cell death modes, including apoptosis, pyroptosis, and autophagy, through its unique chemical and physical properties. Additionally, studies have demonstrated that the combination of LTP with traditional chemotherapy drugs (such as cisplatin and paclitaxel) can enhance the anti-tumor efficacy of the drugs while reducing drug resistance. The combined application of LTP and nanomaterials also shows promising prospects. However, LTP still faces some challenges and limitations in medical applications. Future research needs to further explore the specific applications of LTP in different tumor types, optimize treatment plans, and develop more portable and efficient LTP devices to promote its application in clinical treatment.

Abstract Image

Abstract Image

Abstract Image

低温等离子体在肿瘤治疗中的应用及其作用机制综述。
低温等离子体(LTP)作为一种新兴的癌症治疗技术,由于其独特的物理化学性质和生物效应,显示出巨大的治疗潜力。本文就LTP的基本特点及其在肿瘤治疗中的多种作用机制作一综述。LTP通过其独特的化学和物理性质,可诱导多种细胞死亡模式,包括凋亡、焦亡和自噬。此外,研究表明,LTP与传统化疗药物(如顺铂、紫杉醇)联合使用可以增强药物的抗肿瘤疗效,同时降低耐药。LTP与纳米材料的结合应用也显示出良好的前景。然而,LTP在医疗应用中仍然面临一些挑战和限制。未来的研究需要进一步探索LTP在不同肿瘤类型中的具体应用,优化治疗方案,开发更便携、高效的LTP设备,促进其在临床治疗中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
202
审稿时长
2 months
期刊介绍: Technology in Cancer Research & Treatment (TCRT) is a JCR-ranked, broad-spectrum, open access, peer-reviewed publication whose aim is to provide researchers and clinicians with a platform to share and discuss developments in the prevention, diagnosis, treatment, and monitoring of cancer.
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