The efficacy and safety of stent-assisted coil embolization with the semi-jailing technique in patients with unruptured intracranial aneurysm.

Abstract

Objective: The stent-assisted coiling (SAC) is a well-known procedure for wide neck intracranial aneurysms. To date, the impact of the semi-jailing technique (SJT) on outcomes in patients with SAC remains unknown. This study aims to evaluate the efficacy and safety of SAC using open- or closed-cell stents in patients with unruptured intracranial aneurysms.

Methods: The data of patients treated with SAC between December 2013 and May 2022 was retrospectively investigated. Clinical, aneurysmal, outcomes were compared between patients with and without SJT. The primary outcome was 1-year complete occlusion defined as the Raymond-Roy occlusion classification class I. Safety outcomes included permanent deficits and mortality. Subgroup analysis was also performed regarding open-cell or closed-cell stents.

Results: Among 320 patients with SAC, 220 patients undertook SJT (68.8%). The median age of patients was 61.0 years (interquartile range, 50.3-71.0 years) and 73 were male (22.8%). 1-year complete occlusion was obtained in 221 patients (69.1%). Permanent deficits and mortality were observed in 3 (0.9%) and 1 (0.3%) patient, respectively. Compared to non-SJT, SJT was significantly related to 1-year complete occlusion (73.2% vs. 60.0%, adjusted odds ratio 1.85, 95% confidence interval 1.11-3.09, p=0.02). Safety outcomes showed no significant difference between SJT and non-SJT. Conclusions: The results of this study showed the efficacy and safety of SJT in unruptured intracranial aneurysm patients treated with SAC.