Case Series of Reconstruction Applying NovoSorb Biodegradable Temporising Matrix: Preliminary Practice and Findings in the United Kingdom.

Eplasty Pub Date : 2025-06-05 eCollection Date: 2025-01-01

Simpson Shiu Chung Tam, Kirsten Taylor, Pankaj Patel, Patrick Goon, Manaf Khatib

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Abstract

Background: Biodegradable temporizing matrix (BTM) is a novel synthetic dermal matrix for wound reconstruction and an alternative to biological dermal substitutes such as Integra (Integra LifeSciences). It provides a scaffold for dermal regeneration and acts as a temporizing device prior to skin graft application, reducing the need for autologous tissue donor sites such as local or free-flap transfer.

Methods: This retrospective case series involved 12 patients whose surgery was completed with BTM from October 2021 to February 2023. The inpatient stay, subsequent procedures, and any complications were also reviewed.

Results: The median time for inpatient stay was 3.5 days, and patients who required skin grafts after full BTM integration were treated as a day case. Only 1 case had the complication of postoperative infection.

Conclusions: The study supports the application of BTM products to heal wounds with exposed bone or tendon. This is considered a low-risk option to reduce complications and improve reconstructive and cosmetic outcomes, particularly in the head and neck region.

本刊更多论文

应用NovoSorb可生物降解基质重建的案例系列：在英国的初步实践和发现。

背景：生物可降解临时基质（Biodegradable temporizing matrix， BTM）是一种用于创面重建的新型合成真皮基质，是生物真皮替代品Integra （Integra LifeSciences）的替代品。它为皮肤再生提供了一个支架，并在皮肤移植应用之前作为一个临时装置，减少了对自体组织供体的需求，如局部或自由皮瓣转移。方法：本回顾性病例系列包括12例于2021年10月至2023年2月期间完成BTM手术的患者。住院时间，后续程序和任何并发症也进行了审查。结果：患者住院时间中位数为3.5天，BTM完全融合后需要植皮的患者为1天。仅1例出现术后感染并发症。结论：本研究支持BTM产品在骨或肌腱外露伤口愈合中的应用。这被认为是一种低风险的选择，可以减少并发症，改善重建和美容效果，特别是在头颈部区域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Eplasty

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