Endosymbionts interacting with sex-determining genes and processes.

IF 4.8 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2025-07-12 DOI:10.1016/j.cois.2025.101410

Laura C Fricke, Matthew D Villalta, Amelia Ri Lindsey

引用次数: 0

Abstract

Insects are rich in reproductive diversity and in maternally inherited symbionts. Maternal inheritance has selected for a suite of microbial mechanisms that enhance host fitness and skew sex-ratios in favor of females. Recently, there has been significant progress in characterizing the genetic and cellular mechanisms that these maternally transmitted symbionts use to manipulate insect sex. Significant advances include the identification of specific microbial effector proteins that lead to male-killing, parthenogenesis, and feminization in a range of model and non-model insects. Many of these effectors target similar host processes such as dosage compensation and the sex determination cascade that leads to sex-specific splicing of genes including transformer and double-sex. The independent origins of these endosymbionts and their induced phenotypes facilitate an enhanced understanding of convergent evolution and offer opportunities to investigate the mechanisms driving insect reproductive diversity.

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与性别决定基因和过程相互作用的内共生生物。

昆虫具有丰富的生殖多样性和母系遗传共生体。母体遗传选择了一套微生物机制来增强宿主的适应性，并使性别比例偏向于雌性。最近，在描述这些母体传播的共生体用来操纵昆虫性别的遗传和细胞机制方面取得了重大进展。重大进展包括在一系列模式和非模式昆虫中鉴定导致雄性杀死、孤雌生殖和雌性化的特定微生物效应蛋白。这些效应物中的许多靶向类似的宿主过程，如剂量补偿和性别决定级联，导致基因的性别特异性剪接，包括变性和双性。这些内共生体的独立起源及其诱导的表型有助于加强对趋同进化的理解，并为研究昆虫生殖多样性的驱动机制提供了机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.