Overcoming the Challenges of Intravenous Immunoglobulin Resistance in Kawasaki Disease: A Case Report.

JNMA; journal of the Nepal Medical Association Pub Date : 2024-12-01 Epub Date: 2024-12-31 DOI:10.31729/jnma.8837
Rahul Kumar Chaudhary, Sajjad Ahmed Khan, Raman Kumar Sah, Shreya
{"title":"Overcoming the Challenges of Intravenous Immunoglobulin Resistance in Kawasaki Disease: A Case Report.","authors":"Rahul Kumar Chaudhary, Sajjad Ahmed Khan, Raman Kumar Sah, Shreya","doi":"10.31729/jnma.8837","DOIUrl":null,"url":null,"abstract":"<p><p>Kawasaki disease, extremely rare vasculitis of unknown etiology characterized by inflammation of small to medium sized arteries of multiple systems. This case report enhances the knowledge and management skills of rare clinical conditions. Here we report a case of a 3-month-old infant presented with acute onset fever, rash, non-exudative conjunctivitis and swellings of hands and legs with blood culture positive sepsis and right coronary artery dilatation. The child didn't respond to treatment with the first dose of intravenous immunoglobulin. Therefore, the immunoglobulin resistant Kawasaki disease in infants needs further evaluation and clinical management at tertiary level hospitals.</p>","PeriodicalId":520657,"journal":{"name":"JNMA; journal of the Nepal Medical Association","volume":"62 280","pages":"844-846"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930059/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JNMA; journal of the Nepal Medical Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31729/jnma.8837","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/31 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Kawasaki disease, extremely rare vasculitis of unknown etiology characterized by inflammation of small to medium sized arteries of multiple systems. This case report enhances the knowledge and management skills of rare clinical conditions. Here we report a case of a 3-month-old infant presented with acute onset fever, rash, non-exudative conjunctivitis and swellings of hands and legs with blood culture positive sepsis and right coronary artery dilatation. The child didn't respond to treatment with the first dose of intravenous immunoglobulin. Therefore, the immunoglobulin resistant Kawasaki disease in infants needs further evaluation and clinical management at tertiary level hospitals.

克服川崎病静脉注射免疫球蛋白耐药的挑战:1例报告。
川崎病,一种极为罕见的血管炎,病因不明,以多系统的中小动脉炎症为特征。本病例报告提高了对罕见临床疾病的认识和管理技能。在这里,我们报告一个3个月大的婴儿表现为急性发烧,皮疹,非渗出性结膜炎和肿胀的手和腿与血培养阳性败血症和右冠状动脉扩张。这孩子对第一次静脉注射免疫球蛋白治疗没有反应。因此,婴儿免疫球蛋白耐药川崎病需要在三级医院进一步评估和临床管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信