Eren Öztürk, Serpil Erol, Fügen Vardar-Aker, Şirin Yaşar
{"title":"A Case of Leukocytoclastic Vasculitis Related to Acute Parvovirus B19 Infection.","authors":"Eren Öztürk, Serpil Erol, Fügen Vardar-Aker, Şirin Yaşar","doi":"10.36519/idcm.2025.452","DOIUrl":null,"url":null,"abstract":"<p><p>Parvovirus B19 (PVB19) infection can cause various clinical presentations. While mostly erythema infectiosum, transient aplastic crisis, and fetal hydrops are seen, it rarely causes myocarditis, hepatitis, or vasculitis. We report a patient admitted with fever, fatigue, arthralgia, and rash. Although there was no aetiological clue in the first-line studies, the tests were repeated because of clinical suspicion. Therefore, >4-fold increase in PVB19 IgM titer, IgG seroconversion, and pathological findings led to the diagnosis of leukocytoclastic vasculitis (LCV) related to PVB19. We aimed to emphasize the importance of testing repetition in high clinical suspicion.</p>","PeriodicalId":519881,"journal":{"name":"Infectious diseases & clinical microbiology","volume":"7 2","pages":"209-213"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255897/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious diseases & clinical microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36519/idcm.2025.452","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Parvovirus B19 (PVB19) infection can cause various clinical presentations. While mostly erythema infectiosum, transient aplastic crisis, and fetal hydrops are seen, it rarely causes myocarditis, hepatitis, or vasculitis. We report a patient admitted with fever, fatigue, arthralgia, and rash. Although there was no aetiological clue in the first-line studies, the tests were repeated because of clinical suspicion. Therefore, >4-fold increase in PVB19 IgM titer, IgG seroconversion, and pathological findings led to the diagnosis of leukocytoclastic vasculitis (LCV) related to PVB19. We aimed to emphasize the importance of testing repetition in high clinical suspicion.