Thoracic spinal epidural angiolipoma presenting with progressive paraparesis in an elderly patient.

Surgical neurology international Pub Date : 2025-06-20 eCollection Date: 2025-01-01 DOI:10.25259/SNI_389_2025
Haydar Gok, Kivanc Yangi, Omar Alomari, Uguray Payam Hacisalihoglu
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Abstract

Background: Spinal epidural angiolipomas (SEALs) are rare, benign tumors composed of mature adipocytes and abnormal vasculature, representing only 0.04-1.2% of spinal tumors. Predominantly located in the thoracic epidural space, they often cause progressive neurological deficits due to spinal cord compression, though acute deterioration may occur from hemorrhage or thrombosis. Misdiagnosis is common, and evidence-based management remains limited.

Case description: a 74-year-old woman presented with a 3-month history of progressive paraparesis, gait instability, and left-sided hyperreflexia. Spinal magnetic resonance ımaging revealed an 11 cm posterior epidural mass extending from T3 to T7, causing severe cord compression with myelopathic signal changes. The patient underwent T4-T6 laminectomy with gross total resection of the highly vascular mass. Histopathology confirmed the diagnosis of SEAL. Postoperatively, her symptoms improved, and she was discharged without complications.

Conclusion: This case highlights the importance of recognizing SEALs in differential diagnoses of spinal cord compression, emphasizing meticulous surgical excision for favorable outcomes. A literature review underscores the need for standardized management guidelines for these rare lesions.

以进行性麻痹为表现的胸椎硬膜外血管脂肪瘤1例。
背景:脊髓硬膜外血管脂肪瘤(SEALs)是一种罕见的良性肿瘤,由成熟的脂肪细胞和异常的血管系统组成,仅占脊柱肿瘤的0.04-1.2%。它们主要位于胸椎硬膜外间隙,常因脊髓受压而导致进行性神经功能缺损,但也可因出血或血栓形成而发生急性恶化。误诊是常见的,循证管理仍然有限。病例描述:一名74岁女性,有3个月进行性麻痹、步态不稳和左侧反射亢进病史。脊髓磁共振ımaging显示后侧11 cm硬膜外肿块,从T3延伸至T7,导致脊髓严重受压,伴脊髓病变信号改变。患者行T4-T6椎板切除术,大体切除高度血管性肿块。组织病理学证实了SEAL的诊断。术后症状改善,无并发症出院。结论:本病例强调了在脊髓压迫的鉴别诊断中识别seal的重要性,强调细致的手术切除可获得良好的结果。一篇文献综述强调了对这些罕见病变的标准化管理指南的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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