BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy.

Surgical neurology international Pub Date : 2025-06-06 eCollection Date: 2025-01-01 DOI:10.25259/SNI_284_2025

Stephen Jaffee, Jyothika Mamagdi, Miriam Vaezi, Trent Kite, Bhavika Gupta, Samuel Valleta, Feno Monaco, Nestor Tomycz

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Abstract

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator.

Case description: A 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient's symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias/pain.

Conclusion: Spinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.

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BurstDR™脊髓刺激治疗化疗诱导的周围神经病变。

背景：化疗诱导的周围神经病变（CIPN）是化疗影响癌症幸存者最常见的持续性不良反应之一。除了使用度洛西汀外，没有其他干预措施对这些患者有证实的益处。这里，一个患有多发性骨髓瘤的CIPN患者在植入脊髓刺激器后症状显著减轻。病例描述：64岁男性，有多发性骨髓瘤病史，化疗4年后出现慢性疼痛，随后进行了自体干细胞移植。由于患者的症状难以治疗，他接受了永久性脊髓刺激器的放置，导致小腿疼痛缓解80%，足部感觉异常/疼痛改善60%。结论：脊髓刺激对4年前治疗多发性骨髓瘤的64岁男性CIPN（自体干细胞移植后的CIPN）有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Surgical neurology international

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