Matrix-induced chondrogenesis in the treatment of patients with osteoarthritis of the first metatarsophalangeal: a systematic review.

Abstract

Osteoarthritis of the first metatarsophalangeal joint (MTP) is a common disease of the foot and is associated with decreased range of motion, especially dorsal flexion. It is the second most common pathological condition of the foot, generating pain and stiffness. Treatment for this type of osteoarthritis is still a challenge. Autologous matrix-induced chondrogenesis (AMIC) has emerged as an alternative for treating osteoarthritis while maintaining joint mobility, which has already shown good results in other regions. AMIC has good results in chondral degeneration stages I/II, but it is impossible to assign precise indication criteria for its use. Studies are needed to evaluate advanced stages of degeneration. Good functional and clinical stability have been observed in up to five years of follow-up evaluations. Associations such as cheilectomy and/or osteotomy enhance the results. Currently, there are several different techniques for approaching MTP osteoarthritis and AMIC could be an alternative, however, there is a need for studies evaluating long-term approaches, as well as their complications.