{"title":"Combined approaches to reduce stress and improve livestock well-being: A review","authors":"Ariel Shabtay","doi":"10.1016/j.cstres.2025.100091","DOIUrl":null,"url":null,"abstract":"<div><div>It is well established that various stressors confer hazardous impact on the welfare, health, productive, and reproductive efficiencies of farm animals. Among the major stress stimuli, temperature, transportation, weaning, pathogens, diet quality, and routine handling are cardinal in causing diminished performance of livestock. It is hypothesized that the key to reducing disease incidence and animal discomfort appears to be centered at reducing their response to stress. To this end, strategies that involve thermal conditioning at an early age, dietary interventions, and identification of genetic and biochemical biomarkers to predict the risk for developing stress-related diseases an early, have been studied by our research team during the last two decades as means to alleviate stress in Aves and ruminants. The findings from these studies are presented here to illustrate how the applied strategies have contributed to the following outcomes: 1. In layer hens: Improved regulation of body temperature, reduced mortality rates, and a delayed onset of heat shock protein induction. 2. In cattle: a. mitigation of intestinal diseases and prevention of blood parasite invasion; b. identification of genomic and proteomic biomarkers predictive of susceptibility to bovine respiratory disease, the leading cause of morbidity and mortality among young cattle globally.</div></div>","PeriodicalId":9684,"journal":{"name":"Cell Stress & Chaperones","volume":"30 5","pages":"Article 100091"},"PeriodicalIF":3.2000,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Stress & Chaperones","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1355814525000367","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
It is well established that various stressors confer hazardous impact on the welfare, health, productive, and reproductive efficiencies of farm animals. Among the major stress stimuli, temperature, transportation, weaning, pathogens, diet quality, and routine handling are cardinal in causing diminished performance of livestock. It is hypothesized that the key to reducing disease incidence and animal discomfort appears to be centered at reducing their response to stress. To this end, strategies that involve thermal conditioning at an early age, dietary interventions, and identification of genetic and biochemical biomarkers to predict the risk for developing stress-related diseases an early, have been studied by our research team during the last two decades as means to alleviate stress in Aves and ruminants. The findings from these studies are presented here to illustrate how the applied strategies have contributed to the following outcomes: 1. In layer hens: Improved regulation of body temperature, reduced mortality rates, and a delayed onset of heat shock protein induction. 2. In cattle: a. mitigation of intestinal diseases and prevention of blood parasite invasion; b. identification of genomic and proteomic biomarkers predictive of susceptibility to bovine respiratory disease, the leading cause of morbidity and mortality among young cattle globally.
期刊介绍:
Cell Stress and Chaperones is an integrative journal that bridges the gap between laboratory model systems and natural populations. The journal captures the eclectic spirit of the cellular stress response field in a single, concentrated source of current information. Major emphasis is placed on the effects of climate change on individual species in the natural environment and their capacity to adapt. This emphasis expands our focus on stress biology and medicine by linking climate change effects to research on cellular stress responses of animals, micro-organisms and plants.