Aortic root replacement with a mechanical valve conduit: A single-institutional experience.

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Danial Ahmad, Sarah Yousef, Derek Serna-Gallegos, James A Brown, Johannes Bonatti, David Kaczorowski, Danny Chu, Floyd Thoma, Yisi Wang, Irsa Hasan, Takuya Ogami, Ibrahim Sultan
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Abstract

Background: There is a lack of consensus regarding the best strategy for aortic root replacement with current guidelines supporting the use of mechanical valves in younger patients when a valve repair is not possible. We sought to describe our institutional experience with mechanical aortic root replacement.

Methods: This was a descriptive study using an institutional database of aortic root replacements with a mechanical valve composite graft performed at our center from 2010 to 2022. All patients undergoing aortic root replacements with a mechanical valve were included. Patients undergoing concomitant operations were also included and descriptive statistics were reported.

Results: A total of 217 patients underwent aortic root replacement with a mechanical valve of which women comprised 26.3 %. Bicuspid aortic valves were present in 30.41 % of patients. Aortic dissection and aneurysm were observed in 20.3 % and 35.5 % of patients, respectively, while moderate to severe aortic insufficiency was seen in 62.67 % of patients. Concomitant surgeries included coronary artery bypass graft surgery in 18 % and mitral valve replacement in 7.8 % of patients. Postoperatively, 18 % of patients required prolonged ventilation, while 3.7 % and 3.2 % had postoperative stroke or required dialysis, respectively. Reoperation for mediastinal bleeding was undertaken in 12.4 % of patients. Aortic reintervention over the period of the study was needed in eight patients (3.7 %). The operative/30-day mortality was 6.9 %. Mortality was 17.5 % at a median follow-up of 4 years (1.6-6.1).

Conclusion: Mechanical aortic root replacement is a relatively safe procedure for aortic root pathology with institutional outcomes comparable to other centers.

机械瓣膜导管主动脉根部置换术:单一机构经验。
背景:对于主动脉根部置换术的最佳策略缺乏共识,目前的指南支持在无法进行瓣膜修复的年轻患者中使用机械瓣膜。我们试图描述我们在机械主动脉根部置换术中的机构经验。方法:这是一项描述性研究,使用2010年至2022年在我们中心进行的机械瓣膜复合移植物主动脉根部置换术的机构数据库。所有接受机械主动脉瓣置换术的患者均被纳入研究。同时纳入手术患者,并进行描述性统计。结果:217例患者行主动脉根部机械瓣膜置换术,其中女性占26.3%。30.41%的患者存在双尖瓣主动脉瓣。主动脉夹层和动脉瘤发生率分别为20.3%和35.5%,中重度主动脉不全发生率为62.67%。伴随手术包括18%的冠状动脉搭桥手术和7.8%的二尖瓣置换术。术后,18%的患者需要延长通气时间,3.7%和3.2%的患者术后中风或需要透析。12.4%的患者因纵隔出血再次手术。在研究期间,有8名患者(3.7%)需要主动脉再介入治疗。手术/30天死亡率为6.9%。中位随访4年(1.6-6.1年),死亡率为17.5%。结论:机械主动脉根置换术是一种相对安全的主动脉根病理学治疗方法,其机构预后与其他中心相当。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cardiovascular Revascularization Medicine
Cardiovascular Revascularization Medicine CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.30
自引率
5.90%
发文量
687
审稿时长
36 days
期刊介绍: Cardiovascular Revascularization Medicine (CRM) is an international and multidisciplinary journal that publishes original laboratory and clinical investigations related to revascularization therapies in cardiovascular medicine. Cardiovascular Revascularization Medicine publishes articles related to preclinical work and molecular interventions, including angiogenesis, cell therapy, pharmacological interventions, restenosis management, and prevention, including experiments conducted in human subjects, in laboratory animals, and in vitro. Specific areas of interest include percutaneous angioplasty in coronary and peripheral arteries, intervention in structural heart disease, cardiovascular surgery, etc.
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