Lejla Islamagič, Benedicte Parm Ulhøi, Gorm von Oettingen, Søren Ole Stigaard Cortnum, Anders Rosendal Korshøj, Gaston Schechtmann
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Abstract
Rhombencephalitis (RE) or brainstem encephalitis is a rare but potentially deadly condition. It often affects hosts with weaker or altered immune response. A previously healthy 30-year-old female, three months post-partum, presented with a ten-day history of headache, vomiting, seizures and consciousness deterioration. MRI showed suspect brainstem glioma and hydrocephalus. Initial treatment aimed to reduce high intracranial pressure with an external ventricular drain and high-dose steroids. Despite negative blood cultures, CSF sampling was overlooked as RE was not suspected. The condition proved fatal four days later. Post-mortem histology revealed the RE as the cause of death, but PCR did not show an infectious ethology. With patients in the post-partum period with progressive neurological deterioration and FLAIR2-changes in brainstem MRI, RE should be considered early on.
期刊介绍：
The journal "Acta Neurochirurgica" publishes only original papers useful both to research and clinical work. Papers should deal with clinical neurosurgery - diagnosis and diagnostic techniques, operative surgery and results, postoperative treatment - or with research work in neuroscience if the underlying questions or the results are of neurosurgical interest. Reports on congresses are given in brief accounts. As official organ of the European Association of Neurosurgical Societies the journal publishes all announcements of the E.A.N.S. and reports on the activities of its member societies. Only contributions written in English will be accepted.
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