Predictive value of post-reduction gadolinium-enhanced magnetic resonance imaging in detecting avascular necrosis after closed and open reduction for developmental dysplasia: A minimum 5-year follow-up study.

IF 1.6 4区 医学 Q3 ORTHOPEDICS
Journal of Childrens Orthopaedics Pub Date : 2025-07-06 eCollection Date: 2025-08-01 DOI:10.1177/18632521251350524
Eduardo N Novais, Katharine F Hollnagel, Sarah D Bixby, Mariana G Ferrer, David N Williams, Young-Jo Kim, Florian Schmaranzer
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引用次数: 0

Abstract

Purpose: We aimed to investigate whether globally decreased enhancement on post-reduction gadolinium-enhanced magnetic resonance imaging can predict avascular necrosis after open or closed reduction for developmental dysplasia of the hip.

Methods: We retrospectively analyzed 83 patients (94 hips) who underwent open or closed reduction, with a minimum 5-year follow-up. There were 79 females (84%) with a median age of 7.2 months (interquartile range, 4.8-12). Femoral head enhancement on post-reduction gadolinium-enhanced magnetic resonance imaging was evaluated, and the most recent radiographs were graded using the Kalamchi and MacEwen avascular necrosis classification. Logistic regression was employed to identify predictors of avascular necrosis, and diagnostic performance was calculated.

Results: Of the 94 hips, 51 (54%) exhibited normal enhancement, 20 (21%) had asymmetric enhancement, 11 (12%) had focal decreased enhancement, and 12 (13%) showed global decreased enhancement. At the final follow-up, 63 hips (67%) had no avascular necrosis, and 31 (33%) developed avascular necrosis: 13 (14%) Grade 2, 7 (7%) Grade 3, and 11 (12%) Grade 4 severe avascular necrosis. Multivariate analysis revealed no significant association between globally decreased enhancement, age, type of reduction, or abduction angle with the development of any avascular necrosis or severe avascular necrosis. Sensitivity was low for hips with any avascular necrosis (13%) and severe avascular necrosis (36%), while specificity was 87% and 90%, respectively.

Conclusions: Globally decreased enhancement on post-reduction gadolinium-enhanced magnetic resonance imaging does not necessarily indicate long-term avascular necrosis development following closed or open reduction for developmental dysplasia of the hip. Treatment decisions should not solely rely on this finding. Further research is needed to improve imaging accuracy and assess whether modifying treatment in response to enhancement patterns can reduce avascular necrosis risk.

Level of evidence: Diagnostic, level 3 retrospective cohort.

一项至少5年的随访研究表明,复位后钆增强磁共振成像对发育不良患者闭合和开放复位后缺血性坏死的预测价值。
目的:我们的目的是研究钆增强磁共振成像复位后整体增强降低是否可以预测髋关节发育不良开放性或闭合性复位后的缺血性坏死。方法:我们回顾性分析了83例(94髋)接受开放或闭合复位的患者,随访时间至少为5年。女性79例(84%),中位年龄为7.2个月(四分位数间距为4.8-12)。评估复位后钆增强磁共振成像的股骨头增强,并使用Kalamchi和MacEwen缺血性坏死分级对最近的x线片进行分级。采用Logistic回归来确定缺血性坏死的预测因素,并计算诊断效能。结果:94例髋关节中,51例(54%)表现为正常强化,20例(21%)表现为不对称强化,11例(12%)表现为局部减弱强化,12例(13%)表现为整体减弱强化。在最后的随访中,63例(67%)髋部没有出现缺血性坏死,31例(33%)髋部出现了缺血性坏死:13例(14%)为重度2级,7例(7%)为重度3级,11例(12%)为重度4级缺血性坏死。多变量分析显示,整体增强减弱、年龄、复位类型或外展角度与任何缺血性坏死或严重缺血性坏死的发展没有显著关联。对于有任何缺血性坏死(13%)和严重缺血性坏死(36%)的髋关节,敏感性较低,而特异性分别为87%和90%。结论:复位后钆增强磁共振成像整体增强减弱并不一定表明髋关节发育不良闭合或开放复位后发生长期无血管坏死。治疗决定不应仅仅依赖于这一发现。需要进一步的研究来提高成像的准确性,并评估根据增强模式调整治疗是否可以降低缺血性坏死的风险。证据级别:诊断性,3级回顾性队列。
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来源期刊
Journal of Childrens Orthopaedics
Journal of Childrens Orthopaedics Medicine-Orthopedics and Sports Medicine
CiteScore
2.70
自引率
14.30%
发文量
61
审稿时长
23 weeks
期刊介绍: Aims & Scope The Journal of Children’s Orthopaedics is the official journal of the European Paediatric Orthopaedic Society (EPOS) and is published by The British Editorial Society of Bone & Joint Surgery. It provides a forum for the advancement of the knowledge and education in paediatric orthopaedics and traumatology across geographical borders. It advocates an increased worldwide involvement in preventing and treating musculoskeletal diseases in children and adolescents. The journal publishes high quality, peer-reviewed articles that focus on clinical practice, diagnosis and treatment of disorders unique to paediatric orthopaedics, as well as on basic and applied research. It aims to help physicians stay abreast of the latest and ever-changing developments in the field of paediatric orthopaedics and traumatology. The journal welcomes original contributions submitted exclusively for review to the journal. This continuously published online journal is fully open access and will publish one print issue each year to coincide with the EPOS Annual Congress, featuring the meeting’s abstracts.
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