Obsessive-compulsive disorder in the World Mental Health surveys.

IF 7 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Dan J Stein, Ayelet Meron Ruscio, Yasmin Altwaijri, Wai Tat Chiu, Nancy A Sampson, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Stephanie Chardoul, Oye Gureje, Chiyi Hu, Elie G Karam, John J McGrath, Fernando Navarro-Mateu, Kate M Scott, Juan Carlos Stagnaro, Yolanda Torres, Cristian Vladescu, Jacek Wciórka, Miguel Xavier, Ronald C Kessler
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引用次数: 0

Abstract

Background: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world.

Methods: Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People's Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment.

Results: Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct.

Conclusions: These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.

世界精神卫生调查中的强迫症。
背景:全国调查表明,强迫症(OCD)是一种普遍存在的损害性疾病。然而,关于强迫症的跨国数据很少,低收入和中等收入国家的数据尤其稀少。在这里,我们使用来自世界心理健康调查的数据来描述世界上不同地理区域的一系列国家的强迫症的发病、病程、严重程度和治疗。方法:数据来自10个国家(阿根廷、澳大利亚、哥伦比亚、伊拉克、波兰、中华人民共和国、葡萄牙、罗马尼亚、沙特阿拉伯、西班牙)的普通人口调查,采用一致的研究方案和访谈。共有26136名成年人在面对面访谈中被评估为强迫症,并被纳入本分析。我们研究了6个高收入国家(HICs)和4个低收入或中等收入国家(LMICs)的DSM-IV强迫症的终生和12个月患病率以及发病年龄、持续性、严重程度和治疗情况。我们还调查了社会人口统计学变量和暂时既往精神障碍作为强迫症发病、持续、严重程度和治疗的预测因素。结果:在接受调查的10个国家中,强迫症的终生患病率为4.1%。12个月患病率(3.0%)几乎同样高,表明病程高度持续。发病年龄早,超过80%的强迫症病例开始于成年早期。社区中大多数强迫症病例是轻微的(47.0%)或非常轻微的(27.5%),在耶鲁-布朗强迫症量表中,较小的比例被定为中度(22.9%)或严重(2.7%)。在过去一年中,只有19.8%的强迫症患者接受过心理健康治疗,高收入人群(40.5%)的治疗率远高于中低收入人群(7.0%)。在全球范围内,强迫症通常出现在青春期或成年早期,而背景是早期发生的精神障碍。除了少数例外(例如,先前的社交恐惧症),强迫症的发病、持续、严重程度和治疗的社会人口统计学和精神病理学危险因素是不同的。结论:这些跨国数据强调了早期诊断强迫症和综合评估合并症的重要性;提醒人们注意强迫症是一种治疗不足的疾病,特别是在低收入和中等收入国家;并强调这种经常被忽视的疾病对公共卫生的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Medicine
BMC Medicine 医学-医学:内科
CiteScore
13.10
自引率
1.10%
发文量
435
审稿时长
4-8 weeks
期刊介绍: BMC Medicine is an open access, transparent peer-reviewed general medical journal. It is the flagship journal of the BMC series and publishes outstanding and influential research in various areas including clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. In addition to research articles, the journal also publishes stimulating debates, reviews, unique forum articles, and concise tutorials. All articles published in BMC Medicine are included in various databases such as Biological Abstracts, BIOSIS, CAS, Citebase, Current contents, DOAJ, Embase, MEDLINE, PubMed, Science Citation Index Expanded, OAIster, SCImago, Scopus, SOCOLAR, and Zetoc.
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