Introducing Bayesian Analysis for Clinicians: Sex-Associated Risk Assessment of Intracranial Aneurysms.

Q2 Medicine

Acta neurochirurgica. Supplement Pub Date : 2025-01-01 DOI:10.1007/978-3-031-89844-0_3

Philippe Bijlenga, Georg Ralph Spinner, Marco Scutari, Matteo Delucchi, Sven Hirsch

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引用次数: 0

Abstract

Introduction: Intracranial aneurysms (IAs) are critical vascular defects potentially leading to subarachnoid hemorrhage. A Bayesian framework assists clinicians in assessing IA risks by evaluating multiple factors, including sex, due to its higher prevalence in women.

Methods: This study adopted the Bayesian theorem to quantify IA prevalence and the incidence of subsequent hemorrhage, examining sex as a pivotal risk factor for IA rupture stratification.

Results: The Bayesian analysis revealed a greater incidence of IAs among women yet indicated that sex does not have a significant impact on the rupture risk in diagnosed patients. This finding suggests the necessity of considering other cofactors in risk evaluation.

Conclusions: Bayesian approaches provide clinicians with refined tools for IA risk assessment, emphasizing the complex interplay of various risk factors beyond sex. Acknowledging the limited influence of sex on rupture probability is crucial in guiding IA management. Continuous research is warranted to advance Bayesian methods, improving their clinical applicability and enhancing patient treatment outcomes.

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为临床医生介绍贝叶斯分析：颅内动脉瘤的性别相关风险评估。

颅内动脉瘤是一种严重的血管缺陷，可能导致蛛网膜下腔出血。贝叶斯框架通过评估多种因素（包括性别）来帮助临床医生评估IA风险，因为女性发病率较高。方法：本研究采用贝叶斯定理量化IA患病率和随后出血的发生率，探讨性别是IA破裂分层的关键危险因素。结果：贝叶斯分析显示，在女性中IAs的发生率更高，但表明性别对诊断患者的破裂风险没有显著影响。这一发现表明在风险评估中有必要考虑其他辅助因素。结论：贝叶斯方法为临床医生提供了IA风险评估的完善工具，强调了性别以外各种风险因素的复杂相互作用。认识到性别对破裂概率的影响有限，对指导内窥镜的处理至关重要。继续研究贝叶斯方法，提高其临床适用性，提高患者治疗效果是有必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta neurochirurgica. Supplement Medicine-Surgery

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： In addition to the regular journal, "Acta Neurochirurgica" publishes 3-4 supplement volumes per year. These comprise proceedings of international meetings or other material of general neurosurgical interest.