Single-surgeon outcomes of open radical cystectomy for muscle-invasive bladder cancer: Experience from a tertiary center in Azerbaijan

IF 0.8 Q4 SURGERY
Rashad Sholan , Rufat Aliyev , Seymur Karimov , Jamal Musayev , Anar Almazkhanli , Rahman Ismayilov
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引用次数: 0

Abstract

Objective

Radical cystectomy is the standard treatment for muscle-invasive bladder cancer (MIBC). This study presents the first analysis of open radical cystectomy (ORC) outcomes in Azerbaijan, where robotic surgery is unavailable.

Methods

We retrospectively analyzed 106 patients with non-metastatic MIBC who underwent ORC with bilateral pelvic lymph node dissection and Bricker ileal conduit reconstruction, performed by a single surgeon between 2014 and 2024. Demographic data, comorbidities, operative metrics (duration, blood loss), complications, length of stay, and follow-up data were analyzed.

Results

The cohort's mean age was 64.2 years (72.6 % male), with common comorbidities including hypertension (33 %), diabetes (33 %), and coronary artery disease (24.5 %). The median operative time was 300 min and blood loss was 450 mL. Postoperative complications occurred in 9.4 %, primarily urinary tract infections. No intraoperative complications or in-hospital mortalities occurred. Longer hospital stays were associated with advanced age (p < 0.001), higher body mass index (p = 0.042), longer operative time (p < 0.001), and increased blood loss (p = 0.008). Of all patients, 58.5 % were followed for a median of 71.3 months with no observed recurrences. There were three non-cancer related deaths.

Conclusion

This initial report from Azerbaijan demonstrates acceptable perioperative outcomes for ORC in MIBC, despite the absence of robotic surgery. Our findings emphasize optimizing surgical efficiency, comorbidity management, and strengthening follow-up to enhance patient outcomes in resource-limited settings.
单个外科医生的开放性膀胱根治术治疗肌肉浸润性膀胱癌的结果:来自阿塞拜疆三级中心的经验
目的:根治性膀胱切除术是肌浸润性膀胱癌(MIBC)的标准治疗方法。本研究首次分析了阿塞拜疆开放性根治性膀胱切除术(ORC)的结果,在阿塞拜疆,机器人手术是不可用的。方法回顾性分析2014年至2024年间106例接受ORC合并双侧盆腔淋巴结清扫和Bricker回肠导管重建的非转移性MIBC患者。分析了人口统计数据、合并症、手术指标(持续时间、出血量)、并发症、住院时间和随访数据。结果该队列的平均年龄为64.2岁(男性占72.6%),常见合并症包括高血压(33%)、糖尿病(33%)和冠状动脉疾病(24.5%)。中位手术时间为300分钟,出血量为450毫升。术后并发症发生率为9.4%,主要为尿路感染。无术中并发症及院内死亡。住院时间较长与高龄相关(p <;0.001),较高的体重指数(p = 0.042),较长的手术时间(p <;0.001),出血量增加(p = 0.008)。在所有患者中,58.5%的患者随访时间中位数为71.3个月,未观察到复发。有3例与癌症无关的死亡。来自阿塞拜疆的初步报告表明,尽管没有机器人手术,但MIBC中ORC的围手术期结果是可接受的。我们的研究结果强调在资源有限的情况下优化手术效率、合并症管理和加强随访以提高患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
自引率
0.00%
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审稿时长
38 days
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