Dosimetric investigation of a rotating gamma ray system.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
A Eldib, Veltchev I, L Chen, R Price, C-M Ma
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引用次数: 0

Abstract

Background. Radiosurgery has become an important treatment alternative to surgery for a variety of intracranial lesions. All commercially available systems use convergent beam techniques, but they differ in their treatment delivery methods depending on the machine design and workspace.Purpose. The aim of this work is to investigate a new design for a gamma ray system developed for both intra and extra-cranial stereotactic body radiation therapy (SBRT).Methods. Monte Carlo simulations have been conducted to evaluate rotational radiation delivery using Cobalt-60 gamma beams as compared to linac beams with higher energies. A rotating gamma ray system (RGS), has been modeled using the MCBEAM Monte Carlo code. Treatment plans have been generated utilizing MCPLAN, which is an in-house Monte Carlo treatment planning system. Dosimetric differences between RGS Cobalt-60 beams and Robotic arm linac (RAL) 6 MV beams have been compared in a lung phantom and for previously treated SBRT patients.Results. Results showed that the need for high-energy photon beams decreases with rotational delivery treatments. Cobalt-60 beams could provide a reasonable compromise between beam penetration and penumbra characteristics for lung SBRT applications. The proper combination of available collimator cone sizes and various oblique beam angles allows RGS to shape the isodose lines effectively to match the target volume. The treatment plan quality for RGS has been comparable to that of RAL for both intra- and extra cranial cases. Intensity modulated arcs are feasible with RGS and can add more planning capabilities.Conclusions. The rotating design of the RGS can be of clinical benefit for stereotactic radiation therapy treating cranial cases plus the added ability of treating extra-cranial cases.

旋转伽马射线系统的剂量学研究。
背景:放射外科治疗已成为多种颅内病变的重要替代治疗方法。所有商业上可用的系统都使用会聚光束技术,但根据机器设计和工作空间的不同,它们的治疗递送方法有所不同。& # xD;目的:本研究的目的是研究一种用于颅内和颅外立体定向全身放射治疗(SBRT)的新设计的伽马射线系统。方法:进行蒙特卡罗模拟,以评估使用钴-60伽马光束与具有更高能量的直线光束相比的旋转辐射传递。利用MCBEAM蒙特卡罗代码对旋转伽马射线系统(RGS)进行了建模。治疗计划是利用内部蒙特卡洛治疗计划系统MCPLAN生成的。RGS钴-60光束和机械臂直线(RAL) 6MV光束在肺幻影和先前治疗过的SBRT患者中的剂量学差异进行了比较。结果:我们的研究结果表明,对高能光子束的需求随着旋转传输处理的减少而减少。钴-60光束可以在光束穿透和半暗特性之间提供合理的折衷,用于肺部SBRT应用。准直器锥面尺寸和各种斜光束角度的适当组合使RGS能够有效地塑造等剂量线以匹配目标体积。在颅内和颅外病例中,RGS的治疗计划质量与RAL相当。强度调制弧线与 ;RGS是可行的,可以增加更多的规划功能。结论:旋转RGS的设计对立体定向放射治疗颅骨病例具有临床效益,并增加了治疗颅外病例的能力。
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来源期刊
Biomedical Physics & Engineering Express
Biomedical Physics & Engineering Express RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.80
自引率
0.00%
发文量
153
期刊介绍: BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.
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