Racial/ethnic disparities in time from diagnosis to surgical treatment for type I and type II endometrial carcinomas

IF 4.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Victoria E. Rodriguez , Annie Ro , Michael A. Hoyt , Sora Park Tanjasiri , Robert E. Bristow , Alana M.W. LeBrón
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引用次数: 0

Abstract

Objective

Timeliness of cancer care has been recognized as an indicator of quality of care for numerous cancer sites. Differences in endometrial cancer type may contribute to racial/ethnic disparities in treatment outcomes. This study examines racial/ethnic disparities in time to surgical treatment among type I and type II endometrial cancers.

Methods

We used data from 33,626 women with endometrial cancer in the California Cancer Registry between 2000 and 2019. Descriptive statistics, bivariate analyses, univariate logistic regression models, and multivariate logistic regression models stratified by endometrial cancer type (type I or type II) were performed.

Results

Surgical treatment delays were apparent in 35.3 % (n = 22,487) of type I and 34.6 % (n = 11,139) of type II endometrial cancers; treatment delays varied across racial/ethnic group. Among type I endometrial cancers, multivariable models indicate that American Indian/Alaska Native (odds ratio [OR] 1.47, 95 % CI 1.10–1.97, p < 0.05), Black (OR 1.41, 95 % CI 1.23–1.62, p < 0.001), Hispanic/Latina (OR 1.23, 95 % CI 1.15–1.33, p < 0.001), and Asian or Pacific Islander (OR 1.12, 95 % CI 1.02–1.22, p < 0.01) women had higher odds of experiencing treatment delays compared with White women. Among type II endometrial cancers, multivariable models indicate that Black (OR 1.36, 95 % CI 1.18–1.56, p < 0.001) and Hispanic/Latina (OR 1.15, 95 % CI 1.03–1.28, p < 0.05) women had higher odds of experiencing treatment delays compared with White women.

Conclusions

Targeted interventions are needed to address racial/ethnic disparities in time to surgical treatment for endometrial cancer to ensure equitable access to timely and appropriate cancer care.
I型和II型子宫内膜癌从诊断到手术治疗时间的种族/民族差异
目的癌症治疗的及时性已被认为是许多癌症部位治疗质量的一个指标。子宫内膜癌类型的差异可能导致治疗结果的种族/民族差异。本研究考察了I型和II型子宫内膜癌在手术治疗时间上的种族/民族差异。方法:我们使用了2000年至2019年加州癌症登记处33,626名子宫内膜癌患者的数据。进行描述性统计、双变量分析、单变量logistic回归模型和按子宫内膜癌类型(I型或II型)分层的多变量logistic回归模型。结果I型子宫内膜癌中有35.3% (n = 22,487)、II型子宫内膜癌中有34.6% (n = 11,139)存在明显的手术延迟;治疗延误因种族/民族而异。在I型子宫内膜癌中,多变量模型显示美国印第安人/阿拉斯加原住民(比值比[OR] 1.47, 95% CI 1.10-1.97, p <;0.05),黑色(OR 1.41, 95% CI 1.23-1.62, p <;0.001),西班牙裔/拉丁裔(OR 1.23, 95% CI 1.15-1.33, p <;0.001),亚洲或太平洋岛民(or 1.12, 95% CI 1.02-1.22, p <;0.01)女性经历治疗延迟的几率比白人女性高。在II型子宫内膜癌中,多变量模型显示Black (OR 1.36, 95% CI 1.18-1.56, p <;0.001)和西班牙裔/拉丁裔(OR 1.15, 95% CI 1.03-1.28, p <;0.05)与白人女性相比,女性经历治疗延误的几率更高。结论子宫内膜癌的手术治疗需要有针对性的干预措施,及时解决种族/民族差异,确保公平获得及时和适当的癌症治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gynecologic oncology
Gynecologic oncology 医学-妇产科学
CiteScore
8.60
自引率
6.40%
发文量
1062
审稿时长
37 days
期刊介绍: Gynecologic Oncology, an international journal, is devoted to the publication of clinical and investigative articles that concern tumors of the female reproductive tract. Investigations relating to the etiology, diagnosis, and treatment of female cancers, as well as research from any of the disciplines related to this field of interest, are published. Research Areas Include: • Cell and molecular biology • Chemotherapy • Cytology • Endocrinology • Epidemiology • Genetics • Gynecologic surgery • Immunology • Pathology • Radiotherapy
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