Clinical risk factors associated with cage migration after posterior approaches for lumbar interbody fusion: a 10-year systematic review and meta-analysis.

IF 2.6 3区医学 Q2 CLINICAL NEUROLOGY

European Spine Journal Pub Date : 2025-07-07 DOI:10.1007/s00586-025-09109-z

Haozhong Wang, Changming Xiao, Kaiquan Zhang, Mingzhong Xie, Sen Li

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引用次数: 0

Abstract

Objective: Cage migration (CR) after lumbar interbody fusion may result in intractable complications to patients. This meta-analysis was aimed to figure out risk factors of cage migration after posterior approaches for lumbar interbody fusion.

Methods: Literature was searched in the PubMed, Embase, Web of Science and Cochrane Library between Feb 2013 to Feb 2023. PRISMA guidelines were followed in this review. The keywords used in the search included: cage, retropulsion, migration, lumbar interbody fusion, spinal fusion. Odds ratio (OR) and 95% confidence interval (CI) of a potential risk factor was calculated via RevMan5.4.

Results: 8 studies were finally included in this meta-analysis. 10 risk factors were assessed and the outcome showed that Screw loosening (OR 12.98, 95% CI 4.63 to 36.36, P < 0.01), endplate injury (OR 10.14, 95% CI 5.20 to 19.79, P < 0.01) and pear-shaped disc (OR 4.03, 95% CI 1.41 to 11.55, P < 0.01) were associated with cage migration, and poly-ether-ether-ketone (PEEK) cage (OR 0.51, 95% CI 0.27 to 0.96, P = 0.04) could reduce risk of cage migration.

Conclusion: Screw loosening, endplate injury and pear-shaped disc increased risk of CM after posterior approaches for lumbar interbody fusion, and PEEK cage probably reduce risk of postoperative cage migration.

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腰椎椎体间融合术后路入路后cage移位相关的临床危险因素：10年系统回顾和荟萃分析

目的：腰椎椎体间融合术后椎笼移位（CR）可能导致顽固性并发症。本荟萃分析旨在找出腰椎椎体间融合术后路入路后椎笼移位的危险因素。方法：检索2013年2月- 2023年2月PubMed、Embase、Web of Science和Cochrane Library的文献。本次审查遵循PRISMA指南。搜索中使用的关键词包括：椎笼，后退，移位，腰椎椎间融合，脊柱融合。通过RevMan5.4计算潜在危险因素的优势比（OR）和95%置信区间（CI）。结果：8项研究最终被纳入meta分析。评估了10个危险因素，结果显示螺钉松动（OR 12.98, 95% CI 4.63 ~ 36.36）。结论：螺钉松动、终板损伤和梨形椎间盘增加后路腰椎椎体间融合术后CM的风险，PEEK cage可能降低术后cage移位的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Spine Journal 医学-临床神经学

CiteScore

4.80

自引率

10.70%

发文量

373

审稿时长

2-4 weeks

期刊介绍： "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe