{"title":"Platelet aggregation and platelet-inhibiting drugs.","authors":"G G Nenci","doi":"10.1007/BF02834289","DOIUrl":null,"url":null,"abstract":"<p><p>Platelet function may cause a progression of central gray matter damage after cerebrospinal hemorrhage or trauma because of the thrombotic occlusion of injured vessels or a vasospasm induced by extravasated blood. It has therefore been suggested that antiplatelet drugs could limit the extent of the neurological lesions produced by a spinal trauma. In view of this possibility, the hemostatic functions of platelets and the mechanism of action of antiplatelet drugs are briefly reviewed.</p>","PeriodicalId":77753,"journal":{"name":"Neurochemical pathology","volume":"7 1","pages":"23-32"},"PeriodicalIF":0.0000,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02834289","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurochemical pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02834289","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Platelet function may cause a progression of central gray matter damage after cerebrospinal hemorrhage or trauma because of the thrombotic occlusion of injured vessels or a vasospasm induced by extravasated blood. It has therefore been suggested that antiplatelet drugs could limit the extent of the neurological lesions produced by a spinal trauma. In view of this possibility, the hemostatic functions of platelets and the mechanism of action of antiplatelet drugs are briefly reviewed.
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