Treatment standard: CKD in the geriatric patient.

Elke Schaeffner, Markus Ketteler
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Abstract

The number of older people with CKD is globally increasing. The vast majority of these patients will die before they even have the chance to start kidney replacement therapy. Nevertheless, this clientele of older patients with CKD is often characterized not only by several concomitant diseases but also by frailty. This constellation comes with a general vulnerability and very heterogeneous courses of disease that need to be considered when it comes to diagnosis and treatment. The main difference to younger patients is that therapy and therapy decisions are often preceded by the need for assessments. These can relate to frailty, but also to closely related areas such as cognition, depression or malnutrition among others. The basic therapeutic approaches for CKD treatment in a geriatric patient may not differ fundamentally though from those for younger patients. This also holds true for standard as well as more novel medication administered for nephroprotection. The difference however, lies in the fact that personalized approaches are more frequently required due to survival probability, a more complex mix of chronic conditions, and individual patient's needs and aims. This also applies to the difficult decision as to whether a very old person with CKD G5 should be dialyzed or treated conservatively. Information from different areas should be incorporated into a joint decision-making process, which often requires intensive, patient-centered communication about the patient's preferences and prioritized treatment goals, psychosocial factors and their home environment, as well as their medical needs and prognosis.

治疗标准:老年CKD患者。
老年CKD患者的数量在全球范围内不断增加。这些患者中的绝大多数甚至在开始肾脏替代治疗之前就会死亡。然而,这类老年CKD患者的特点往往不仅有几种伴随疾病,而且身体虚弱。这一组合具有普遍的易感性和非常不同的病程,在诊断和治疗时需要加以考虑。对年轻患者的主要区别在于,治疗和治疗决定通常在需要评估之前进行。这些问题可能与身体虚弱有关,但也与认知、抑郁或营养不良等密切相关的领域有关。老年CKD患者的基本治疗方法可能与年轻患者的基本治疗方法没有根本区别。这也适用于标准的以及更新颖的肾保护药物。然而,不同之处在于,由于生存概率、慢性病的更复杂组合以及个体患者的需求和目标,更频繁地需要个性化的方法。这也适用于一个非常老的CKD G5患者是否应该进行透析或保守治疗的困难决定。来自不同领域的信息应纳入联合决策过程,这通常需要就患者的偏好和优先治疗目标、社会心理因素和家庭环境,以及他们的医疗需求和预后进行深入的、以患者为中心的沟通。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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