Trends in metabolic risk factors control among adults with type 2 diabetes: A comparative study of 2018 and 2021.

Primary care diabetes Pub Date : 2025-07-02 DOI:10.1016/j.pcd.2025.06.008

Fereshteh Baygi, Peter Haastrup, Helene Støttrup Andersen, Sonja Wehberg, Jens Søndergaard

{"title":"Trends in metabolic risk factors control among adults with type 2 diabetes: A comparative study of 2018 and 2021.","authors":"Fereshteh Baygi, Peter Haastrup, Helene Støttrup Andersen, Sonja Wehberg, Jens Søndergaard","doi":"10.1016/j.pcd.2025.06.008","DOIUrl":null,"url":null,"abstract":"Aims: This study aims to analyze recent trends in managing major metabolic risk factors among type 2 diabetes patients (T2D) over time.Methods: We used data from the Danish Adult Diabetes Registry (DVDD) on health indicators in 2018 and 2021. Information about medication was found using Danish National Prescription Registry (DNPR). Cut points for abnormal values of the included health indicators were identified from the revised National Cholesterol Education Program Adult Treatment Panel III criteria. Correspondingly, reached target levels were defined. A logistic regression model based on generalized estimating equations was fitted to evaluate the difference between 2018 and 2021.Results: We included 24,343 and 18,027 observations in 2018 and 2021, respectively. Longitudinal analyses showed statistically significant improvement in Low density lipoprotein, Blood pressure, triglycerides, and Glycated hemoglobin control overtime. The use of glucose-lowering and lipid-lowering medications, and antihypertensive medication increased. Obesity declined significantly overtime. Subgroup analyses highlighted improvement in metabolic control across age groups, with TG control declining in T2D patients over 60 years.Conclusions: We found statistically significant improvement in metabolic risk factor control and medication use over time. Despite progress in managing LDL, BP, and HbA1c, challenges remain in Blood pressure and triglycerides control.","PeriodicalId":94177,"journal":{"name":"Primary care diabetes","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Primary care diabetes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.pcd.2025.06.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: This study aims to analyze recent trends in managing major metabolic risk factors among type 2 diabetes patients (T2D) over time.

Methods: We used data from the Danish Adult Diabetes Registry (DVDD) on health indicators in 2018 and 2021. Information about medication was found using Danish National Prescription Registry (DNPR). Cut points for abnormal values of the included health indicators were identified from the revised National Cholesterol Education Program Adult Treatment Panel III criteria. Correspondingly, reached target levels were defined. A logistic regression model based on generalized estimating equations was fitted to evaluate the difference between 2018 and 2021.

Results: We included 24,343 and 18,027 observations in 2018 and 2021, respectively. Longitudinal analyses showed statistically significant improvement in Low density lipoprotein, Blood pressure, triglycerides, and Glycated hemoglobin control overtime. The use of glucose-lowering and lipid-lowering medications, and antihypertensive medication increased. Obesity declined significantly overtime. Subgroup analyses highlighted improvement in metabolic control across age groups, with TG control declining in T2D patients over 60 years.

Conclusions: We found statistically significant improvement in metabolic risk factor control and medication use over time. Despite progress in managing LDL, BP, and HbA1c, challenges remain in Blood pressure and triglycerides control.

查看原文本刊更多论文

成人2型糖尿病患者代谢危险因素控制趋势：2018年和2021年的比较研究

目的：本研究旨在分析2型糖尿病患者（T2D）主要代谢危险因素管理的最新趋势。方法：我们使用了丹麦成人糖尿病登记处（DVDD） 2018年和2021年健康指标的数据。使用丹麦国家处方登记处（DNPR）查找有关药物的信息。从修订后的国家胆固醇教育计划成人治疗小组III标准中确定了所包括健康指标异常值的切点。相应地，确定了达到的目标水平。拟合基于广义估计方程的logistic回归模型，评估2018年与2021年的差异。结果：我们在2018年和2021年分别纳入了24,343和18,027项观察结果。纵向分析显示，随着时间的推移，低密度脂蛋白、血压、甘油三酯和糖化血红蛋白的控制有统计学意义的改善。降糖、降脂药物和抗高血压药物的使用增加。随着时间的推移，肥胖率显著下降。亚组分析强调了各年龄组代谢控制的改善，60岁以上T2D患者的TG控制下降。结论：我们发现随着时间的推移，代谢危险因素控制和药物使用有统计学意义的改善。尽管在控制LDL、BP和HbA1c方面取得了进展，但在血压和甘油三酯控制方面仍然存在挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Primary care diabetes

自引率

0.00%

发文量