Surgery partially mitigates a 2-decade decline in health-related quality of life for adolescents with idiopathic scoliosis undergoing spinal fusion at 2 years.

IF 1.6 Q3 CLINICAL NEUROLOGY
Adam A Jamnik, Anne-Marie Datcu, Emily Lachmann, Karl Rathjen, Megan Johnson, David Thornberg, Chan-Hee Jo, Brandon Ramo
{"title":"Surgery partially mitigates a 2-decade decline in health-related quality of life for adolescents with idiopathic scoliosis undergoing spinal fusion at 2 years.","authors":"Adam A Jamnik, Anne-Marie Datcu, Emily Lachmann, Karl Rathjen, Megan Johnson, David Thornberg, Chan-Hee Jo, Brandon Ramo","doi":"10.1007/s43390-025-01136-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to evaluate how 2-year postoperative SRS scores for patients with adolescent idiopathic scoliosis (AIS) who underwent spine fusion have evolved over time.</p><p><strong>Methods: </strong>Single center, retrospective review of AIS patients who underwent fusion between 2002 and 2020. Patients were included if they completed SRS questionnaires preoperatively and 2-years postoperatively (21-49 months). The SRS has seven scoreable domains: Pain, Appearance, Activity, Mental Health, Subtotal (calculated with the four previous domains), Satisfaction, and Total Score. Domain score range from 1 to 5 (worst-best). Multivariable linear regressions were performed on 2-year SRS domain scores. The primary variable was calendar year of SRS completion, but variables also included: preoperative SRS scores, gender, race, age, and time since surgery (months). Subsequently multivariable linear regressions were performed for the change in SRS scores between preoperative and 2-year.</p><p><strong>Results: </strong>Seven hundred eighty seven patients (83.7% female, age 14.3 ± 2.0) were included in this study. Of the variables included, preoperative SRS scores, gender, race, and time since surgery contributed significantly to the regression models. More recent calendar years for SRS completion were associated with worse Mental Health and Activity domain scores (coefficient = - 0.010, p = 0.0432; coefficient = - 0.007, p = 0.0340). Each additional year was associated with a ~ 0.01 decline in Mental Health and Activity scores. Regression analysis between preop and 2-year scores found that patients with more recent SRS completion years had greater improvements in Pain and Subtotal scores (coefficient = 0.014, p = 0.013, coefficient = 0.009, p = 0.023).</p><p><strong>Conclusion: </strong>AIS patients undergoing spinal fusion in more recent years report worse HRQoL in the Activity and Mental Health domains postoperatively. However, Pain and Subtotal scores had greater improvements from preoperative to 2-year, suggesting a mitigating effect of surgery in the setting of declining preoperative scores.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine deformity","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s43390-025-01136-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: The purpose of this study is to evaluate how 2-year postoperative SRS scores for patients with adolescent idiopathic scoliosis (AIS) who underwent spine fusion have evolved over time.

Methods: Single center, retrospective review of AIS patients who underwent fusion between 2002 and 2020. Patients were included if they completed SRS questionnaires preoperatively and 2-years postoperatively (21-49 months). The SRS has seven scoreable domains: Pain, Appearance, Activity, Mental Health, Subtotal (calculated with the four previous domains), Satisfaction, and Total Score. Domain score range from 1 to 5 (worst-best). Multivariable linear regressions were performed on 2-year SRS domain scores. The primary variable was calendar year of SRS completion, but variables also included: preoperative SRS scores, gender, race, age, and time since surgery (months). Subsequently multivariable linear regressions were performed for the change in SRS scores between preoperative and 2-year.

Results: Seven hundred eighty seven patients (83.7% female, age 14.3 ± 2.0) were included in this study. Of the variables included, preoperative SRS scores, gender, race, and time since surgery contributed significantly to the regression models. More recent calendar years for SRS completion were associated with worse Mental Health and Activity domain scores (coefficient = - 0.010, p = 0.0432; coefficient = - 0.007, p = 0.0340). Each additional year was associated with a ~ 0.01 decline in Mental Health and Activity scores. Regression analysis between preop and 2-year scores found that patients with more recent SRS completion years had greater improvements in Pain and Subtotal scores (coefficient = 0.014, p = 0.013, coefficient = 0.009, p = 0.023).

Conclusion: AIS patients undergoing spinal fusion in more recent years report worse HRQoL in the Activity and Mental Health domains postoperatively. However, Pain and Subtotal scores had greater improvements from preoperative to 2-year, suggesting a mitigating effect of surgery in the setting of declining preoperative scores.

手术在一定程度上缓解了特发性脊柱侧凸2岁时接受脊柱融合术的青少年20年来健康相关生活质量的下降。
目的:本研究的目的是评估接受脊柱融合的青少年特发性脊柱侧凸(AIS)患者术后2年SRS评分随时间的变化。方法:对2002 - 2020年间行融合术的AIS患者进行单中心、回顾性分析。如果患者术前和术后2年(21-49个月)完成SRS问卷,则纳入患者。SRS有七个可计分的领域:疼痛、外表、活动、心理健康、小计(根据前四个领域计算)、满意度和总分。域得分范围从1到5(最差最好)。对2年SRS域评分进行多变量线性回归。主要变量为完成SRS的日历年,但变量还包括:术前SRS评分、性别、种族、年龄和手术后时间(月)。随后对术前和2年内SRS评分的变化进行多变量线性回归。结果:共纳入787例患者,其中女性83.7%,年龄14.3±2.0岁。在纳入的变量中,术前SRS评分、性别、种族和手术后时间对回归模型有显著影响。完成SRS的日历年越近,心理健康和活动域得分越差(系数= - 0.010,p = 0.0432;系数= - 0.007,p = 0.0340)。每增加一年,心理健康和活动得分就会下降~ 0.01。术前和2年评分的回归分析发现,SRS完成时间越近的患者在Pain和Subtotal评分方面的改善更大(系数= 0.014,p = 0.013,系数= 0.009,p = 0.023)。结论:近年来接受脊柱融合术的AIS患者在术后活动和心理健康领域的HRQoL较差。然而,从术前到2年,疼痛和次总计评分有更大的改善,表明手术在术前评分下降的情况下有缓解作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.20
自引率
18.80%
发文量
167
期刊介绍: Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信