Living Donor Uterus Transplantation.

IF 4.7 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Obstetrics and gynecology Pub Date : 2025-07-03 DOI:10.1097/AOG.0000000000005987

Masato Tamate, Giuliano Testa, Laura Divine, Johanna Bayer, Liza Johannesson

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Abstract

Background: For women with absolute uterine factor infertility, uterus transplantation represents the closest solution to normal gestation and delivery. It is a temporary transplant; the uterine graft is removed after completion of childbearing. The uterus transplant journey involves multiple surgical and medical steps.

Technique: The surgical steps include living or deceased donor hysterectomy, transplant of the uterine graft, cesarean delivery, and graft hysterectomy. The medical steps include immunosuppressive treatment, in vitro fertilization, and pregnancy. In this video, we show a living donor uterus transplant, including donor hysterectomy, back-table preparation of the uterine graft, and recipient transplant surgery. The video highlights the surgical steps of the procedure.

Experience: Between September 2016 and January 2025, 36 women underwent uterus transplantation at Baylor University Medical Center, resulting in the birth of 26 children to date.

Conclusion: Uterus transplantation is associated with successful births of healthy children.

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活体供体子宫移植。

背景：对于子宫绝对因素性不孕的妇女，子宫移植是最接近正常妊娠和分娩的解决方案。这是一个暂时的移植；子宫移植物在分娩结束后被移除。子宫移植过程包括多个手术和医疗步骤。技术：手术步骤包括活体或已故供体子宫切除术、移植物子宫移植、剖宫产和移植物子宫切除术。医疗步骤包括免疫抑制治疗、体外受精和怀孕。在这个视频中，我们展示了一个活体供体子宫移植，包括供体子宫切除术，子宫移植的后台准备和受体移植手术。这段视频重点介绍了手术步骤。经验：2016年9月至2025年1月，36名妇女在贝勒大学医学中心接受了子宫移植手术，迄今已有26名儿童出生。结论：子宫移植与健康儿的成功分娩有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics and gynecology 医学-妇产科学

CiteScore

11.10

自引率

4.20%

发文量

867

审稿时长

1 months

期刊介绍： "Obstetrics & Gynecology," affectionately known as "The Green Journal," is the official publication of the American College of Obstetricians and Gynecologists (ACOG). Since its inception in 1953, the journal has been dedicated to advancing the clinical practice of obstetrics and gynecology, as well as related fields. The journal's mission is to promote excellence in these areas by publishing a diverse range of articles that cover translational and clinical topics. "Obstetrics & Gynecology" provides a platform for the dissemination of evidence-based research, clinical guidelines, and expert opinions that are essential for the continuous improvement of women's health care. The journal's content is designed to inform and educate obstetricians, gynecologists, and other healthcare professionals, ensuring that they stay abreast of the latest developments and best practices in their field.