Groin hernia.

IF 76.9 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Jacob Rosenberg, Sarfaraz Baig, David C Chen, Joep Derikx
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引用次数: 0

Abstract

Groin hernias are among the most common indications for surgery worldwide, affecting both men and women, with a significantly higher prevalence in men. These hernias occur when intra-abdominal contents protrude through a weakened area in the groin region, most commonly as inguinal or femoral hernias. The pathogenesis of groin hernias is a complex interplay of genetic predisposition, connective tissue abnormalities and mechanical strain. While watchful waiting is an option for some asymptomatic patients, surgical repair remains the definitive treatment, with both open and minimally invasive techniques available. Tension-free mesh repair has significantly reduced the overall recurrence rates and is now the standard approach in adults in most clinics. However, tissue-based repairs are still preferred in select populations such as children, teenagers and those in resource-limited settings. Advances in laparoscopic and robotic-assisted techniques offer benefits such as reduced postoperative pain and faster recovery. Despite surgical advancements, complications, such as chronic postoperative pain and recurrence, continue to pose challenges. Future research aims to refine surgical techniques, look at mesh-related complications, develop bioengineered meshes and explore the genetic basis of hernia formation.

腹股沟疝。
腹股沟疝是世界范围内最常见的手术指征之一,影响男性和女性,男性的患病率明显更高。当腹内内容物通过腹股沟区域的薄弱区域突出时,就会发生这些疝,最常见的是腹股沟疝或股疝。腹股沟疝的发病机制是遗传易感性、结缔组织异常和机械应变的复杂相互作用。虽然观察等待是一些无症状患者的一种选择,但手术修复仍然是最终的治疗方法,开放和微创技术都是可用的。无张力补片修复显著降低了整体复发率,现在是大多数诊所成人的标准方法。然而,在儿童、青少年和资源有限的人群中,基于组织的修复仍然是首选。腹腔镜和机器人辅助技术的进步提供了诸如减少术后疼痛和更快恢复等好处。尽管手术进展,并发症,如慢性术后疼痛和复发,继续构成挑战。未来的研究目标是改进手术技术,研究网状物相关并发症,开发生物工程网状物,探索疝形成的遗传基础。
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来源期刊
Nature Reviews Disease Primers
Nature Reviews Disease Primers Medicine-General Medicine
CiteScore
76.70
自引率
0.20%
发文量
75
期刊介绍: Nature Reviews Disease Primers, a part of the Nature Reviews journal portfolio, features sections on epidemiology, mechanisms, diagnosis, management, and patient quality of life. The editorial team commissions top researchers — comprising basic scientists and clinical researchers — to write the Primers, which are designed for use by early career researchers, medical students and principal investigators. Each Primer concludes with an Outlook section, highlighting future research directions. Covered medical specialties include Cardiology, Dermatology, Ear, Nose and Throat, Emergency Medicine, Endocrinology, Gastroenterology, Genetic Conditions, Gynaecology and Obstetrics, Hepatology, Haematology, Infectious Diseases, Maxillofacial and Oral Medicine, Nephrology, Neurology, Nutrition, Oncology, Ophthalmology, Orthopaedics, Psychiatry, Respiratory Medicine, Rheumatology, Sleep Medicine, and Urology.
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