Evaluation of Cardiac Autonomic Function in Patients With Alteration in Thyroid Hormones: Systematic Literature Review.

IF 2.4 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Clinical Endocrinology Pub Date : 2025-07-03 DOI:10.1111/cen.15299

Marianne Lucena da Silva, Nádia Martins de Paula Souza, Miguel Luciano Rodrigues da Silva Júnior, Brenda Gabriele Dantas Pinto Vieira, Liana Barbaresco Gomide Matheus, Aline Teixeira Alves, Katiane da Costa Cunha

{"title":"Evaluation of Cardiac Autonomic Function in Patients With Alteration in Thyroid Hormones: Systematic Literature Review.","authors":"Marianne Lucena da Silva, Nádia Martins de Paula Souza, Miguel Luciano Rodrigues da Silva Júnior, Brenda Gabriele Dantas Pinto Vieira, Liana Barbaresco Gomide Matheus, Aline Teixeira Alves, Katiane da Costa Cunha","doi":"10.1111/cen.15299","DOIUrl":null,"url":null,"abstract":"Background: Thyroid hormonal disorders are widely discussed in the literature. These dysfunctions also influence the modulation of the cardiovascular system due to alterations in the autonomic nervous system, affecting heart rate variability.Objectives: To verify the influence of thyroidian hormonal dysfunctions on the modulation of cardiac autonomic activity.Methods: A systematic review was carried out to search for studies used in the electronic databases Virtual Health Library (VHL), Scielo, Pubmed via Medline, Cochrane, Embase, Scopus, Web of Science, Cinahl and SPORTDiscus, without restrictions how many years. For this review, we have considered experimental studies carried out with human beings that will analyse the variability of heart rate in the thyroid hormone diseases.Results: Ten thousand two hundred ninety-eight items found, 15 included, which were non-randomised clinical trials that assessed heart rate variability domains. I note that patients affected by hypothyroidism or hyperthyroidism have a reduction in heart rate variability, reflecting a decrease in the adaptive capacity of the heart.Conclusion: Both hypothyroidism and hyperthyroidism affect cardiac autonomic modulation, resulting in a reduction in heart rate variability. However, there were differences in relation to the availability of frequency and time data.","PeriodicalId":10346,"journal":{"name":"Clinical Endocrinology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Endocrinology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/cen.15299","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Thyroid hormonal disorders are widely discussed in the literature. These dysfunctions also influence the modulation of the cardiovascular system due to alterations in the autonomic nervous system, affecting heart rate variability.

Objectives: To verify the influence of thyroidian hormonal dysfunctions on the modulation of cardiac autonomic activity.

Methods: A systematic review was carried out to search for studies used in the electronic databases Virtual Health Library (VHL), Scielo, Pubmed via Medline, Cochrane, Embase, Scopus, Web of Science, Cinahl and SPORTDiscus, without restrictions how many years. For this review, we have considered experimental studies carried out with human beings that will analyse the variability of heart rate in the thyroid hormone diseases.

Results: Ten thousand two hundred ninety-eight items found, 15 included, which were non-randomised clinical trials that assessed heart rate variability domains. I note that patients affected by hypothyroidism or hyperthyroidism have a reduction in heart rate variability, reflecting a decrease in the adaptive capacity of the heart.

Conclusion: Both hypothyroidism and hyperthyroidism affect cardiac autonomic modulation, resulting in a reduction in heart rate variability. However, there were differences in relation to the availability of frequency and time data.

查看原文本刊更多论文

甲状腺激素改变患者心脏自主神经功能的评价：系统文献综述。

背景：甲状腺激素紊乱在文献中被广泛讨论。由于自主神经系统的改变，这些功能障碍也影响心血管系统的调节，影响心率变异性。目的：探讨甲状腺激素功能障碍对心脏自主神经活动调节的影响。方法：对电子数据库Virtual Health Library （VHL）、Scielo、Pubmed via Medline、Cochrane、Embase、Scopus、Web of Science、Cinahl和SPORTDiscus中使用的研究进行系统综述，不限制研究的年数。在这篇综述中，我们考虑了对人类进行的实验研究，这些研究将分析甲状腺激素疾病中心率的变异性。结果：发现了一万二千九十八项，其中包括15项，这是评估心率变异性领域的非随机临床试验。我注意到，受甲状腺功能减退或甲状腺功能亢进影响的患者心率变异性降低，反映了心脏适应能力的下降。结论：甲状腺功能减退和甲状腺功能亢进均影响心脏自主调节，导致心率变异性降低。然而，在频率和时间数据的可用性方面存在差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Endocrinology 医学-内分泌学与代谢

CiteScore

6.40

自引率

3.10%

发文量

192

审稿时长

1 months

期刊介绍： Clinical Endocrinology publishes papers and reviews which focus on the clinical aspects of endocrinology, including the clinical application of molecular endocrinology. It does not publish papers relating directly to diabetes care and clinical management. It features reviews, original papers, commentaries, correspondence and Clinical Questions. Clinical Endocrinology is essential reading not only for those engaged in endocrinological research but also for those involved primarily in clinical practice.